Summary Background Various tools are obtainable for the detection of Pneumocystis jirovecii, among them qPCR promising highest sensitivity. A novel molecular method is commercially available, the loop‐mediated isothermal amplification (LAMP) assay. Objectives We compared the performance of the LAMP eazyplex® Pneumocystis jirovecii with the RealStar ...
Ulrike Scharmann +5 more
wiley +1 more source
Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia
Pneumocystis pneumonia (PCP) caused by the opportunistic fungal agent Pneumocystis jirovecii (formerly Pneumocystis carinii) continues to cause illness and death in HIV-infected patients.
Charles Ben Beard +6 more
doaj +1 more source
Pneumocystis carinii pneumonia (PCP) atau Pneumocystis jirovecii pneumonia merupakan infeksi oportunistik yang dapat terjadi pada pasien immunocompromised. Pada pasien dengan HIV, PCP merupakan infeksi oportunistik tersering terutama pada pasien dengan CD4 kurang dari 200 sel/ul.
Dewi Rizki Agustina +4 more
openaire +2 more sources
A Rare Case of Splenic Pneumocystis jirovecii in a HIV‐Positive Patient
Introduction. Human immunodeficiency virus (HIV) positive individuals with the CD4 count less than 200 cells/mm3 are at risk for opportunistic infections. Pneumocystis jirovecii, a fungal pathogen, is a common cause of opportunistic infections with predominantly pulmonary involvement. Disseminated P.
Hafsa Abbas +6 more
wiley +1 more source
Improved detection of Pneumocystis jirovecii in upper and lower respiratory tract specimens from children with suspected pneumocystis pneumonia using real-time PCR: a prospective study [PDF]
BACKGROUND: Pneumocystis pneumonia (PCP) is a major cause of hospitalization and mortality in HIV-infected African children. Microbiologic diagnosis relies predominantly on silver or immunofluorescent staining of a lower respiratory tract (LRT) specimens
Catherine M Samuel +7 more
core +2 more sources
Extra-pulmonary Pneumocystis jiroveci infection: a case report
In physical examination abdominal tenderness, gate disturbance and penile herpetic lesions were detected. Decreased disc height at T11-T12 level was detected in chest X-ray.
Mehrdad Bakhshayesh Karam +1 more
doaj +1 more source
Identification and Functional Ascertainment of the Pneumocystis jirovecii Potential Drug Targets Gsc1 and Kre6 Involved in Glucan Synthesis. [PDF]
The most efficient drug against the human pathogenic fungus Pneumocystis jirovecii is cotrimoxazole targeting the folate biosynthesis. However, resistance toward it is emerging and adverse effects occur in some patients.
Cissé, O.H. +3 more
core +1 more source
Clinical characteristics of pneumonia in non-HIV patients and prognostic factors including microbiological genotypes [PDF]
Background The number of patients with non-HIV Pneumocystis pneumonia (PCP) is increasing with widespread immunosuppressive treatment. We investigated the clinical characteristics of non-HIV PCP and its association with microbiological ...
Yasufumi Matsumura +10 more
core +1 more source
Functional Characterization of
Fungi in the genus Pneumocystis live in the lungs of mammals, where they can cause a fatal pneumonia (PCP [Pneumocystis pneumonia]) in hosts with compromised immune systems.
Melanie T. Cushion +5 more
doaj +1 more source
Epidemiology of Pneumocystis jirovecii Pneumonia and (Non-)use of Prophylaxis
Objectives:Pneumocystis jirovecii pneumonia (PCP) is an AIDS-defining illness. In patients with HIV, the benefit of PCP prophylaxis is well-defined when the CD4 T-cell count decreases below 200 cells/μL.
Albert Dunbar +10 more
doaj +1 more source

