Results 121 to 130 of about 7,584 (199)

Interaction of pneumolysin-sufficient and -deficient isogenic variants of Streptococcus pneumoniae with human respiratory mucosa [PDF]

, 1995
C F Rayner, A D Jackson, A Rutman, A Dewar, Timothy J. Mitchell, Peter W. Andrew, Peter Cole, Robert Wilson   +7 more
openalex   +1 more source

Serotype-independent protective activity of recombinant pneumolysin in a model of systemic infection caused by <i>Streptococcus pneumoniae</i> serotypes 4 and 6B

, 2022
D. S. Vorobyev, Е. С. Петухова, Yu. V. Volokh, O. М. Afanasyeva, M. M. Tokarskaya, A. Yu. Leonova, O. V. Zhigunova, И. Б. Семенова, Н. Ф. Гаврилова, I. V. Yakovleva, N. E. Yastrebova   +10 more
openalex   +2 more sources

Pharmacologic depletion of border-associated macrophages worsens disease in a mouse model of meningitis. [PDF]

Acta Neuropathol Commun
Dyckhoff-Shen S, Masouris I, Pfister HW, Völk S, Hammerschmidt S, Klein M, Koedel U.   +6 more
europepmc   +1 more source

A novel drug that reduces pneumococcal toxicity by targeting pneumolysin (PLY): efficacy of the traditional Chinese medicine <i>Radix Paeoniae Alba</i>. [PDF]

Front Pharmacol
Xu Y, Han J, Zhou Y, Sun L.
europepmc   +1 more source

Antibodies against polysaccharide type 3 and pneumococcal proteins demonstrate synergistic protective effect in a highly virulent type 3 invasive disease model in mice. [PDF]

Front Immunol
Stevenson TC, Burke H, Roggensack SE, Pratt A, Hossain A, Ghosh P, Besin G, Lu Y, Zhang F, Malley R, Sebastian S.   +10 more
europepmc   +1 more source

Protection against Pneumococcal Pneumonia in Mice by Monoclonal Antibodies to Pneumolysin

, 2004
Marı́a del Mar Garcı́a-Suárez, María Dolores Cima‐Cabal, Noélia Flórez-Fernández, Pilar García, Rafael Cernuda‐Cernuda, Aurora Astudillo, Fernando Vázquez, Juan R. de los Toyos, Francisco Javier Méndez   +8 more
openalex   +2 more sources

<i>In vitro</i> and <i>in vivo</i> evaluation of humanized monoclonal antibodies targeting pneumolysin. [PDF]

Microbiol Spectr
Song L, Hu H, Huang J, Li H, Zhang Y, Ma N, Song Z.   +6 more
europepmc   +1 more source

Neurotoxicity of Pneumolysin, a Major Pneumococcal Virulence Factor, Involves Calcium Influx and Depends on Activation of p38 Mitogen-Activated Protein Kinase

, 2002
Argyrios K. Stringaris, Jens Geisenhainer, Friederike Bergmann, Christoph Balshüsemann, Unaa Lee, Gregor Zysk, Timothy J. Mitchell, Bernhard U. Keller, U. Kuhnt, Joachim Gerber, Annette Spreer, Mathias Bähr, Uwe Michel, Roland Nau   +13 more
openalex   +2 more sources

Clarithromycin Inhibits Pneumolysin Production via Downregulation of ply Gene Transcription despite Autolysis Activation

, 2021
Hisanori Domon, Toshihito Isono, Takumi Hiyoshi, Hikaru Tamura, Karin Sasagawa, Tomoki Maekawa, Satoru Hirayama, Katsunori Yanagihara, Yutaka Terao   +8 more
openalex   +1 more source

Endothelial ENaC as a repressor of oxidative stress and a guardian of lung capillary barrier function in bacterial and viral pneumonia. [PDF]

Front Physiol
Eaton DC, Romero MJ, Matthay MA, Hamacher J, Advani A, Wolf A, Abu Mraheil M, Chakraborty T, Stepp DW, Belin de Chantemèle EJ, Kutlar A, Kraft F, Zeitlinger M, Kranke P, Frank S, Su Y, Verin AD, Fulton DJR, Ushio-Fukai M, Fukai T, Lucas R.   +20 more
europepmc   +1 more source