Results 91 to 100 of about 392,151 (262)

Evaluation of Pneumococcal Load in Blood by Polymerase Chain Reaction for the Diagnosis of Pneumococcal Pneumonia in Young Children in the PERCH Study. [PDF]

, 2017
BACKGROUND.: Detection of pneumococcus by lytA polymerase chain reaction (PCR) in blood had poor diagnostic accuracy for diagnosing pneumococcal pneumonia in children in 9 African and Asian sites.
Ahmed, Dilruba, Antonio, Martin, Awori, Juliet O, Baggett, Henry C, Baillie, Vicky L, Brooks, W Abdullah, Chipeta, James, Deloria Knoll, Maria, Deluca, Andrea N, Dione, Michel, Driscoll, Amanda J, Feikin, Daniel R, Hammitt, Laura L, Higdon, Melissa M, Howie, Stephen RC, Jatapai, Anchalee, Karron, Ruth A, Kotloff, Karen L, Levine, Orin S, Madhi, Shabir A, Mazumder, Razib, Moore, David P, Morpeth, Susan C, Murdoch, David R, Mwansa, James, Nyongesa, Sammy, O'Brien, Katherine L, Park, Daniel E, PERCH Study Group, Prosperi, Christine, Scott, J Anthony G, Seidenberg, Phil, Siludjai, Duangkamon, Sow, Samba O, Tamboura, Boubou, Thea, Donald M, Watson, Nora L, Zeger, Scott L   +37 more
core   +1 more source

Evaluation of the pneumococcal urinary antigen test (PUT): a retrospective study

Fujita Medical Journal, 2021
Objectives: To determine the usefulness of the pneumococcal urinary antigen test (PUT) and to describe the characteristics of pneumococcal pneumonia.
Tatsuyoshi Yokoi, Kazunobu Kuwabara, Kiyotaka Ono, Yusuke Kito, Kenichi Kato, Keisuke Kato, Masahiro Hirose, Rieko Kondo, Takahiko Horiguchi   +8 more
doaj   +1 more source

The Safety of 12‐Weekly Monitoring of Neutrophil Count in Long‐Term Clozapine Patients

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Clozapine is the only truly effective treatment for refractory schizophrenia, but its use is constrained by the requirements for frequent monitoring of neutrophil counts. In the UK during the COVID‐19 pandemic, the frequency of clozapine blood monitoring was reduced in some units from 4‐weekly to 12‐weekly. We aimed to investigate
David Taylor, Siobhan Gee, Marinka Helthuis, Ebenezer Oloyede   +3 more
wiley   +1 more source

A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]

, 2011
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Bewley, M.A., Chain, B., Deretic, V., Dockrell, D.H., Francis, S.E., Kroemer, G., Marriott, H.M., Mitchell, T.J., Read, R.C., Tulone, C., Whyte, M.K.B.   +10 more
core   +4 more sources

Herd effects of child vaccination with pneumococcal conjugate vaccine against pneumococcal non-invasive community-acquired pneumonia: What is the evidence?

Human Vaccines & Immunotherapeutics, 2017
Quantification of pneumococcal conjugate vaccines (PCVs) herd effects are mainly performed on invasive pneumococcal disease (IPD) but there is conflicting evidence regarding herd effects of PCVs on non-IPD pneumococcal community-acquired pneumonia.
Cornelis H. van Werkhoven
doaj   +1 more source

Pneumococcal pneumonia prevalence among adults with severe acute respiratory illness in Thailand - comparison of Bayesian latent class modeling and conventional analysis

BMC Infectious Diseases, 2019
Background Determining the etiology of pneumonia is essential to guide public health interventions. Diagnostic test results, including from polymerase chain reaction (PCR) assays of upper respiratory tract specimens, have been used to estimate prevalence
Ying Lu, Lawrence Joseph, Patrick Bélisle, Pongpun Sawatwong, Anchalee Jatapai, Toni Whistler, Somsak Thamthitiwat, Wantana Paveenkittiporn, Supphacoke Khemla, Chris A. Van Beneden, Henry C. Baggett, Christopher J. Gregory   +11 more
doaj   +1 more source

Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection [PDF]

, 2004
Streptococcus pneumoniae is an important human pathogen responsible for high mortality and morbidity worldwide. The susceptibility to pneumococcal infections is controlled by as yet unknown genetic factors.
Jonczyk, Magda S., Simon, Michelle, Kumar, Saumya, Fernandes, Vitor E., Sylvius, Nicolas, Mallon, Ann-Marie, Denny, Paul, Andrew, Peter W.   +7 more
core   +5 more sources

A Retrospective Study of Pneumococcal Pneumonia in Hospitalized Patients Aged ≥65 Years in Izumo, Japan: 2010 to 2014

International Journal of General Medicine, 2023
Megumi Hamaguchi,1 Yukari Tsubata,1 Ken Yoshihara,1 Mika Nakao,1 Yoshihiro Amano,1 Kazuhisa Nakashima,1 Takamasa Hotta,2 Tamio Okimoto,1 Shunichi Hamaguchi,3 Akihisa Sutani,4 Takeshi Isobe1 1Division of Medical Oncology and Respiratory Medicine ...
Hamaguchi M, Tsubata Y, Yoshihara K, Nakao M, Amano Y, Nakashima K, Hotta T, Okimoto T, Hamaguchi S, Sutani A, Isobe T   +10 more
doaj  

Cross-sectional study on attitudes among general practitioners towards pneumococcal vaccination for middle-aged and elderly population in Hong Kong. [PDF]

PLoS ONE, 2013
OBJECTIVE: To study the attitudes among general practitioners towards pneumococcal vaccination for middle-aged (50-64) and elderly population (over 65) in Hong Kong and the factors affecting their decision to advise pneumococcal vaccination for those age
Lancelot W H Mui, Alvin Y S Chan, Albert Lee, John Lee   +3 more
doaj   +1 more source

Retrospective database analysis for clinical diagnoses commonly associated with pneumococcal diseases in the Malaysian healthcare system over a 3-year period (2013–2015)

BMC Infectious Diseases
Background Pneumococcal disease caused by Streptococcus pneumoniae is an important cause of morbidity and mortality across all ages, particularly in younger children and older adults. Here, we describe pneumococcal disease hospitalizations at Ministry of
Saravanan S. R. Sundaramurthy, Kristen E. Allen, Mark A. Fletcher, Kok Fui Liew, Boekhtiar Borhanuddin, Mohammad Ali, Graciela Morales, Bradford Gessner, Jerusha Naidoo, Jo Southern   +9 more
doaj   +1 more source