Results 51 to 60 of about 409,686 (231)

Burden of pneumococcal disease in children in Cuba before the introduction of a novel pneumococcal conjugate vaccine

Journal of Global Health Reports, 2019
# Background The Cuban heptavalent conjugate pneumococcal vaccine will be introduced for children beginning in 2020. We estimated the burden of pneumococcal cases and deaths in children 1-59 months in 2015.
Nivaldo Linares-Pérez, Brian Wahl, Misladys Rodriguez, Gilda Toraño, María E. Toledo-Romaní   +4 more
doaj   +1 more source

Prevalence, Clinical Severity, and Serotype Distribution of Pneumococcal Pneumonia Among Adults Hospitalized With Community-Acquired Pneumonia in Tennessee and Georgia, 2018–2022

Clinical Infectious Diseases
Introduction Understanding the pneumococcal serotypes causing community-acquired pneumonia (CAP) is essential for evaluating the impact of pneumococcal vaccines.
W. Self, Kelly D Johnson, J. J. Resser, Cynthia G Whitney, A. Baughman, Mai Kio, C. Grijalva, J. Traenkner, Jakea Johnson, Karen F. Miller, Christina A Rostad, Inci Yildirim, Luis Salazar, Ralph Tanios, S. Swan, Yuwei Zhu, Jin H. Han, Thomas Weiss, Craig S. Roberts, Nadine G. Rouphael, Wesley H J Jackson Adrienne Carlos G Jakea Karen F Sydney Self Resser Baughman Grijalva Johnson Miller Swan , W. Self, J. J. Resser, A. Baughman, C. Grijalva, Jakea Johnson, Karen F. Miller, S. Swan, Yuwei Zhu, Jin H. Han, Sabrina Shipman, Nadine G. Rouphael, Cynthia G Whitney, Mai Kio, J. Traenkner, Christina A Rostad, Inci Yildirim, Laurel Bristow, Luis Salazar, Zayna Al-Husein, Evan Anderson, Ifeyinwa Benyeogor, Andrew Cheng, Jong-Ha Choi, Khalel De Castro, Ana Drobeniuc, Kieffer Hellmeister, Ariel Kay, Matthew Lee, Vikash Patel, Olivia D Reese, Veronica E Smith, Ralph Tanios, E. Taylor, Megan Taylor, Wesley Washington, Cecilia Zhang, Kelly D Johnson, Thomas Weiss, Craig S. Roberts, Madelyn Ruggieri   +60 more
semanticscholar   +1 more source

The Annexin A1/FPR2 pathway controls the inflammatory response and bacterial dissemination in experimental pneumococcal pneumonia

The FASEB Journal, 2019
Streptococcus pneumoniae is a major cause of community‐acquired pneumonia leading to high mortality rates. Inflammation triggered by pneumococcal infection is necessary for bacterial clearance but must be spatially and temporally regulated to prevent ...
M. G. Machado, L. Tavares, Geovanna V. Santos Souza, C. Queiroz-Junior, Fernando R Ascenção, M. E. Lopes, Cristiana C Garcia, G. Menezes, M. Perretti, R. C. Russo, M. Teixeira, L. Sousa   +11 more
semanticscholar   +1 more source

An economic analysis of a pneumococcal vaccine programme in people aged over 64 years in a developed country setting. [PDF]

, 2005
BACKGROUND: Polysaccharide pneumococcal vaccination for older adults is being introduced in developed country settings. Evidence of protection by this vaccine against pneumococcal pneumonia, or confirmation that illness and death from bacteraemia are ...
Cutts, Felicity T, Hall, Andrew J, Mangtani, Punam, Roberts, Jennifer A   +3 more
core   +1 more source

Impact of pneumococcal conjugate vaccines on hospitalizations for pneumonia in the United States

Expert Review of Vaccines, 2019
Introduction: Pneumonia is one of the leading causes of morbidity and mortality among children and older adults. Pneumococcal conjugate vaccines (PCVs) were introduced into the US routine infant vaccination schedule leading to substantial reductions of ...
Andrew D. Wiese, M. Griffin, Carlos G. Grijalva   +2 more
semanticscholar   +1 more source

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue [PDF]

, 2011
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria.
AD Reynolds, AM Faria, C Jokinen, C Laine, C O'Mahony, Carlos Javier Orihuela, D Bogaert, DM Musher, EJ Novak, EK Mulholland, EM Laughlin, G Oldenhove, H Christensen, HM Foy, HW Lim, I Rudan, JC Paton, Jeffrey Pido-Lopez, JL Round, JN Stoop, K Wing, KA Robinson, L Strauss, L Weiss, M Hara, M Hussain, M Lipsitch, M Livingston, M Quigley, MJ Butte, MJ van Kempen, MW Mureithi, N Iikuni, Neil A. Williams, PC Hill, PR Myles, Q Zhang, Q Zhang, Q Zhang, R Austrian, R Malley, R Malley, RM Wong, Robert S. Heyderman, S Hori, S Paust, S Rapola, S Read, S Sakaguchi, S Sakaguchi, SE Sandner, SK Obaro, SQ Crome, T Sturniolo, T Takahashi, Timothy J. Mitchell, V Davenport, William W. Kwok, X Zhang, Y Belkaid, Y Cong, YJ Lu, Z Zhang   +62 more
core   +3 more sources

Pathogenesis and prevention of risk of cardiovascular events in patients with pneumococcal community‐acquired pneumonia

Journal of Internal Medicine, 2019
It is now well recognized that cardiovascular events (CVE) occur quite commonly, both in the acute phase and in the long‐term, in patients with community‐acquired pneumonia (CAP).
C. Feldman, S. Normark, B. Henriques‐Normark, R. Anderson   +3 more
semanticscholar   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

The anticipated severity of a "1918-like" influenza pandemic in contemporary populations: the contribution of antibacterial interventions. [PDF]

PLoS ONE, 2012
Recent studies have shown that most of deaths in the 1918 influenza pandemic were caused by secondary bacterial infections, primarily pneumococcal pneumonia.
Yu-Wen Chien, Bruce R Levin, Keith P Klugman   +2 more
doaj   +1 more source

MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal Pneumonia

Cells, 2023
Community-acquired pneumonia remains a major contributor to global communicable disease-mediated mortality. Neutrophils play a leading role in trying to contain bacterial lung infection, but they also drive detrimental pulmonary inflammation, when ...
Cengiz Goekeri, Peter Pennitz, Wibke Groenewald, Ulrike Behrendt, Holger Kirsten, Christian M. Zobel, Sarah Berger, Gitta A. Heinz, Mir-Farzin Mashreghi, Sandra-Maria Wienhold, Kristina Dietert, Anca Dorhoi, Achim D. Gruber, Markus Scholz, Gernot Rohde, Norbert Suttorp, CAPNETZ Study Group, Martin Witzenrath, Geraldine Nouailles   +18 more
doaj   +1 more source