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Apoptosis in Pneumovirus Infection [PDF]

open access: yesViruses, 2013
Pneumovirus infections cause a wide spectrum of respiratory disease in humans and animals. The airway epithelium is the major site of pneumovirus replication.
Reinout A. Bem   +2 more
doaj   +3 more sources

First Detection and Genetic Characterization of Swine Orthopneumovirus from Domestic Pig Farms in the Republic of Korea [PDF]

open access: yesViruses, 2023
Novel swine orthopneumovirus (SOV) infections have been identified in pigs in the USA and some European countries but not in Asian countries, including South Korea, to date.
Jonghyun Park   +10 more
doaj   +2 more sources

Opposite Responses of Interferon and Proinflammatory Cytokines Induced by Human Metapneumovirus and Respiratory Syncytial Virus in Macrophages [PDF]

open access: yesPathogens
Macrophages are a principal pulmonary source of type I and III interferons (IFNs), initiating and coordinating the early antiviral response to respiratory viral infections.
Iván Martínez-Espinoza   +1 more
doaj   +2 more sources

Respiratory Syncytial Virus: The Urgent Need for Innovative Preventive Strategies [PDF]

open access: yesPediatric Reports
Respiratory Syncytial Virus (RSV) is a medium-sized enveloped Pneumovirus belonging to the Paramyxoviridae family [...]
Fabrizio Virgili   +2 more
doaj   +2 more sources

Vaccine Development for Human Pneumoviruses [PDF]

open access: yesVaccines
Background: Pneumoviruses are etiologic agents of respiratory tract infections and a major cause of morbidity and mortality worldwide, particularly affecting young children, the elderly, and individuals with underlying clinical conditions.
Elhadji Birane Mboup   +4 more
doaj   +2 more sources

Global Extension and Predominance of Human Metapneumovirus A2 Genotype with Partial G Gene Duplication

open access: yesViruses, 2022
Human metapneumovirus (HMPV) is an important respiratory pathogen and is divided in two main groups (A and B). HMPV strains with partial duplications (111-nt and 180-nt duplication) of the G gene have been reported in recent years.
Juan Carlos Muñoz-Escalante   +3 more
doaj   +1 more source

Sendai Virus-Vectored Vaccines That Express Envelope Glycoproteins of Respiratory Viruses

open access: yesViruses, 2021
Human respiratory syncytial virus (HRSV), human metapneumovirus (HMPV), and human parainfluenza viruses (HPIVs) are leading causes of respiratory disease in young children, the elderly, and individuals of all ages with immunosuppression.
Charles J. Russell, Julia L. Hurwitz
doaj   +1 more source

Full-genome analysis of a canine pneumovirus causing acute respiratory disease in dogs, Italy. [PDF]

open access: yesPLoS ONE, 2014
An outbreak of canine infectious respiratory disease (CIRD) associated to canine pneumovirus (CnPnV) infection is reported. The outbreak occurred in a shelter of the Apulia region and involved 37 out of 350 dogs that displayed cough and/or nasal ...
Nicola Decaro   +9 more
doaj   +1 more source

Long-Term Pulmonary Dysfunction by Hyperoxia Exposure during Severe Viral Lower Respiratory Tract Infection in Mice

open access: yesPathogens, 2022
Viral-induced lower respiratory tract infection (LRTI), mainly by respiratory syncytial virus (RSV), causes a major health burden among young children and has been associated with long-term respiratory dysfunction.
Thijs A. Lilien   +6 more
doaj   +1 more source

The HRA2pl fusion peptide exerts in vitro antiviral activity against human respiratory paramyxoviruses and pneumoviruses

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Acute respiratory infections are a group of diseases caused by viruses, bacteria, and parasites that mainly affect children until the age of 5 and immunocompromised senior adults.
Uriel Cruz Meza   +5 more
doaj   +1 more source

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