In the aging population, lower urinary tract (LUT) dysfunction is common and often leads to storage and voiding difficulties classified into overlapping symptom syndromes.
Lori A. Birder+12 more
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AU-Rich Long 3′ Untranslated Region Regulates Gene Expression in Bacteria
3′ untranslated regions (3′ UTRs) and particularly long 3′ UTRs have been shown to act as a new class of post-transcriptional regulatory element. We previously reported that hmsT mRNA stability is negatively regulated by the 3′ UTR of hmsT in Yersinia ...
Ju-Ping Zhao+3 more
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Characterization of the RNase R association with ribosomes [PDF]
BACKGROUND: In this study we employed the TAP tag purification method coupled with mass spectrometry analysis to identify proteins that co-purify with Escherichia coli RNase R during exponential growth and after temperature downshift.
Cecilia M Arraiano+2 more
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Import of Non-Coding RNAs into Human Mitochondria: A Critical Review and Emerging Approaches
Mitochondria harbor their own genetic system, yet critically depend on the import of a number of nuclear-encoded macromolecules to ensure their expression.
Damien Jeandard+5 more
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Structural insights into the dimeric human PNPase revealing why the disease-linked mutants exhibit lower RNA import and degradation activities [PDF]
Bagher Golzarroshan, Hanna S. Yuan
openalex +2 more sources
Enzymatic Synthesis and Fractionation of Fluorescent PolyU RNAs
The physical properties of viral-length polyuridine (PolyU) RNAs, which cannot base-pair and form secondary structures, are compared with those of normal-composition RNAs, composed of comparable numbers of each of A, U, G and C nucleobases.
Christian Beren+4 more
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Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is accompanied by morphological, functional, and metabolic alterations before acquisition of full pluripotency.
Ken Nishimura+13 more
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The majority of Escherichia coli mRNAs undergo post-transcriptional modification in exponentially growing cells [PDF]
Polyadenylation of RNAs by poly(A) polymerase I (PAP I) in Escherichia coli plays a significant role in mRNA decay and general RNA quality control. However, many important features of this system, including the prevalence of polyadenylated mRNAs in the ...
Aiso+35 more
core +2 more sources
Acquirement of cold sensitivity by quadruple deletion of the cspA family and its suppression by PNPase S1 domain in Escherichia coli [PDF]
Bing Xia, Haiping Ke, Masayori Inouye
openalex +1 more source
RNA Degradation in Staphylococcus aureus: Diversity of Ribonucleases and Their Impact
The regulation of RNA decay is now widely recognized as having a central role in bacterial adaption to environmental stress. Here we present an overview on the diversity of ribonucleases (RNases) and their impact at the posttranscriptional level in the ...
Rémy A. Bonnin, Philippe Bouloc
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