RNase P Branches Out from RNP to Protein: Organelle-Triggered Diversification? [PDF]
RNase P is the enzyme that removes 5′ leader sequences from precursor tRNAs. Remarkably, in most organisms, RNase P is a ribonucleoprotein particle where the RNA component is responsible for catalysis. In this issue of Genes \u26 Development, Gutmann and
Borah, Sumit +2 more
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AU-Rich Long 3′ Untranslated Region Regulates Gene Expression in Bacteria
3′ untranslated regions (3′ UTRs) and particularly long 3′ UTRs have been shown to act as a new class of post-transcriptional regulatory element. We previously reported that hmsT mRNA stability is negatively regulated by the 3′ UTR of hmsT in Yersinia ...
Ju-Ping Zhao +3 more
doaj +1 more source
Cytoplasmic RNA decay pathways - enzymes and mechanisms [PDF]
RNA decay plays a crucial role in post-transcriptional regulation of gene expression. Work conducted over the last decades has defined the major mRNA decay pathways, as well as enzymes and their cofactors responsible for these processes. In contrast, our
Dziembowski, Andrzej +2 more
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Import of Non-Coding RNAs into Human Mitochondria: A Critical Review and Emerging Approaches
Mitochondria harbor their own genetic system, yet critically depend on the import of a number of nuclear-encoded macromolecules to ensure their expression.
Damien Jeandard +5 more
doaj +1 more source
Polynucleotide phosphorylase exonuclease and polymerase activities on single-stranded DNA ends are modulated by RecN, SsbA and RecA proteins [PDF]
Bacillus subtilis pnpA gene product, polynucleotide phosphorylase (PNPase), is involved in double-strand break (DSB) repair via homologous recombination (HR) or non-homologous end-joining (NHEJ).
Aguilera +75 more
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Enzymatic Synthesis and Fractionation of Fluorescent PolyU RNAs
The physical properties of viral-length polyuridine (PolyU) RNAs, which cannot base-pair and form secondary structures, are compared with those of normal-composition RNAs, composed of comparable numbers of each of A, U, G and C nucleobases.
Christian Beren +4 more
doaj +1 more source
Knocking out ACR2 does not affect arsenic redox status in Arabidopsis thaliana: implications for As detoxification and accumulation in plants [PDF]
Peer reviewedPublisher ...
David E Salt +8 more
core +7 more sources
Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is accompanied by morphological, functional, and metabolic alterations before acquisition of full pluripotency.
Ken Nishimura +13 more
doaj +1 more source
RNA Degradation in Staphylococcus aureus: Diversity of Ribonucleases and Their Impact
The regulation of RNA decay is now widely recognized as having a central role in bacterial adaption to environmental stress. Here we present an overview on the diversity of ribonucleases (RNases) and their impact at the posttranscriptional level in the ...
Rémy A. Bonnin, Philippe Bouloc
doaj +1 more source
Yersiniae Virulence Factors: Type III Secretion System [PDF]
Several Gram-negative pathogenic bacteria have evolved a complex protein secretion system termed the Type Three Secretion System (TTSS) to deliver bacterial effector proteins into host-cells that then modulate host-cellular functions.
Blanco, Jessica
core +1 more source

