Results 131 to 140 of about 5,147 (230)

RNase P Branches Out from RNP to Protein: Organelle-Triggered Diversification? [PDF]

open access: yes, 2012
RNase P is the enzyme that removes 5′ leader sequences from precursor tRNAs. Remarkably, in most organisms, RNase P is a ribonucleoprotein particle where the RNA component is responsible for catalysis. In this issue of Genes \u26 Development, Gutmann and
Borah, Sumit   +2 more
core   +3 more sources

AU-Rich Long 3′ Untranslated Region Regulates Gene Expression in Bacteria

open access: yesFrontiers in Microbiology, 2018
3′ untranslated regions (3′ UTRs) and particularly long 3′ UTRs have been shown to act as a new class of post-transcriptional regulatory element. We previously reported that hmsT mRNA stability is negatively regulated by the 3′ UTR of hmsT in Yersinia ...
Ju-Ping Zhao   +3 more
doaj   +1 more source

Cytoplasmic RNA decay pathways - enzymes and mechanisms [PDF]

open access: yes, 2016
RNA decay plays a crucial role in post-transcriptional regulation of gene expression. Work conducted over the last decades has defined the major mRNA decay pathways, as well as enzymes and their cofactors responsible for these processes. In contrast, our
Dziembowski, Andrzej   +2 more
core   +1 more source

Import of Non-Coding RNAs into Human Mitochondria: A Critical Review and Emerging Approaches

open access: yesCells, 2019
Mitochondria harbor their own genetic system, yet critically depend on the import of a number of nuclear-encoded macromolecules to ensure their expression.
Damien Jeandard   +5 more
doaj   +1 more source

Polynucleotide phosphorylase exonuclease and polymerase activities on single-stranded DNA ends are modulated by RecN, SsbA and RecA proteins [PDF]

open access: yes, 2011
Bacillus subtilis pnpA gene product, polynucleotide phosphorylase (PNPase), is involved in double-strand break (DSB) repair via homologous recombination (HR) or non-homologous end-joining (NHEJ).
Aguilera   +75 more
core   +2 more sources

Enzymatic Synthesis and Fractionation of Fluorescent PolyU RNAs

open access: yesBio-Protocol, 2018
The physical properties of viral-length polyuridine (PolyU) RNAs, which cannot base-pair and form secondary structures, are compared with those of normal-composition RNAs, composed of comparable numbers of each of A, U, G and C nucleobases.
Christian Beren   +4 more
doaj   +1 more source

A Role for KLF4 in Promoting the Metabolic Shift via TCL1 during Induced Pluripotent Stem Cell Generation

open access: yesStem Cell Reports, 2017
Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is accompanied by morphological, functional, and metabolic alterations before acquisition of full pluripotency.
Ken Nishimura   +13 more
doaj   +1 more source

RNA Degradation in Staphylococcus aureus: Diversity of Ribonucleases and Their Impact

open access: yesInternational Journal of Genomics, 2015
The regulation of RNA decay is now widely recognized as having a central role in bacterial adaption to environmental stress. Here we present an overview on the diversity of ribonucleases (RNases) and their impact at the posttranscriptional level in the ...
Rémy A. Bonnin, Philippe Bouloc
doaj   +1 more source

Yersiniae Virulence Factors: Type III Secretion System [PDF]

open access: yes, 2008
Several Gram-negative pathogenic bacteria have evolved a complex protein secretion system termed the Type Three Secretion System (TTSS) to deliver bacterial effector proteins into host-cells that then modulate host-cellular functions.
Blanco, Jessica
core   +1 more source

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