Results 141 to 150 of about 47,146 (309)

Counting glomeruli in human kidney specimens using ex vivo MRI without contrast agents

Magnetic Resonance in Medicine, Volume 94, Issue 6, Page 2519-2528, December 2025.
Abstract Purpose The total number of glomeruli is an important indicator of kidney function and susceptibility to disease. Glomeruli, however, are difficult to image using MRI without contrast enhancement. For this reason, previous studies have used cationic ferritin as a contrast agent to detect glomeruli in ex vivo and in vivo perfused kidneys.
Nyoman D. Kurniawan, Aurel J. Amar, Luise A. Cullen‐McEwen, Alexander N. Combes, Raeesah Hayatudin, Andrew J. Kassianos, Jiaxin Du, Sarah E. Gazzard, Helen G. Healy, Wendy E. Hoy, John F. Bertram, David C. Reutens   +11 more
wiley   +1 more source

Nicotine Induces Podocyte Apoptosis through Increasing Oxidative Stress.

PLoS ONE, 2016
BackgroundCigarette smoking plays an important role in the progression of chronic kidney disease (CKD). Nicotine, one of the major components of cigarette smoking, has been demonstrated to increase proliferation of renal mesangial cells.
Xiqian Lan, Rivka Lederman, Judith M Eng, Seyedeh Shadafarin Marashi Shoshtari, Moin A Saleem, Ashwani Malhotra, Pravin C Singhal   +6 more
doaj   +1 more source

Aryl Hydrocarbon Receptor in Health and Disease

MedComm, Volume 6, Issue 11, November 2025.
Based on the structure and ligands of AhR, this review introduces the AhR‐related signaling pathways and their roles in health and diseases. Agonists and antagonists of AhR as well as new strategies for treatment using the microbial–AhR axis are summarized. A prospect was made for the future use of AhR as a therapeutic target.
Haonan Li, Yufeng Fan, Jizheng Liu, Shumin Dong, Bin Wen, Yunfei Zhang, Xiaocui Wang, Xuemei Duan, Ying Hu, Ze Yan, Huifeng Shang, Yukai Jing   +11 more
wiley   +1 more source

Protamine Sulfate and Oxidant Stress Cause Similar Changes in Hsp27 Intracellular Distribution in Cultured Podocytes [PDF]

, 1999
Richard F. Ransom, William E. Smoyer
openalex   +1 more source

For the eye altering, alters the all [PDF]

, 2015
C
Boey, Olivier, Bogaert, Anne-Marie, De Scheerder, Marie-Angélique, Mahieu, Elien, Vanuytsel, Johan   +4 more
core   +1 more source

Unveiling Vasculature‐Associated Lymphoid Tissue (VALT) in Goats: A Novel Player in Kidney Inflammation

Veterinary Medicine and Science, Volume 11, Issue 6, November 2025.
Vasculature‐Associated Lymphoid Tissue (VALT) is a significant tertiary lymphoid tissue that contributes to kidney inflammation and has not yet been identified in ruminants. Our study revealed that VALT in goats consists of typical immune cells, including macrophages, T cells, B cells and high endothelial venules.
Md. Abdul Masum, Subrato Biswas, Rupa Akter   +2 more
wiley   +1 more source

Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis [PDF]

, 2001
Dontscho Kerjaschki
openalex   +2 more sources

Effects of BSF on Podocyte Apoptosis via Regulating the ROS-Mediated PI3K/AKT Pathway in DN

Journal of Diabetes Research, 2019
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD). The ROS-mediated PI3K/AKT pathway plays a key role in podocyte apoptosis and DN progression. Our previous study demonstrated that Baoshenfang (BSF) can decrease proteinuria
Fang-qiang Cui, Yue-Fen Wang, Yan-bin Gao, Yuan Meng, Zhen Cai, Cun Shen, Zhi-qiang Liu, Xin-can Jiang, Wen-jing Zhao   +8 more
doaj   +1 more source

Blockade of cannabinoid CB1 receptors potentiates the anti‐fibrotic effects mediated by SGLT2 inhibition in a mouse model of diabetic nephropathy

British Journal of Pharmacology, Volume 182, Issue 21, Page 5355-5377, November 2025.
Background and purpose Diabetic nephropathy (DN) is a common complication of diabetes. Current treatments include renin‐angiotensin‐aldosterone system (RAAS) blockers and sodium‐glucose co‐transporter 2 (SGLT2) inhibitors. The cannabinoid CB1 receptor is a potential therapeutic target.
Océane Pointeau, Awa Isma Ba, Audrey Geissler, Romain Barbosa, Abhishek Basu, Arif Muhammad, Marina Nivot, Maéva Loriot, Julia Leemput, Patricia Passilly‐Degrace, Sébastien Causse, Laurent Demizieux, Hélène François, Bruno Vergès, Jianmin Duan, Geneviève Gaucher, Michael Harvey, Pascal Degrace, Glenn Crater, Resat Cinar, Tony Jourdan   +20 more
wiley   +1 more source

Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate [PDF]

, 2000
Bryan L. Wharram, Meera Goyal, Patrick J. Gillespie, Jocelyn Wiggins, David B. Kershaw, Lawrence B. Holzman, Robert C. Dysko, Thomas L. Saunders, Linda C. Samuelson, Roger C. Wiggins   +9 more
openalex   +1 more source