Results 161 to 170 of about 33,221 (207)

Structural dynamics, pathogenic mechanisms, and therapeutic targeting of the NLRP3 inflammasome in lupus nephritis. [PDF]

Front Immunol
Sun H, Xie X, Ma M, Li H, Jin Y, Zhang M.   +5 more
europepmc   +1 more source

LncRNA GATA3-AS1-mediated miR-2116-5p interaction modulates TCF12 and contributes to podocyte dysfunction in childhood nephrotic syndrome. [PDF]

Clinics (Sao Paulo)
Tong X, Zhao Y, Huang P.
europepmc   +1 more source

Deubiquitinating enzymes in kidney diseases: Molecular mechanisms, pathological roles and therapeutic opportunities (Review). [PDF]

Mol Med Rep
Li Q, Ni Y, Li Z, Li J, Wang L.
europepmc   +1 more source

Podocyte-specific acid sphingomyelinase overexpression promotes gasdermin D dependent pyroptosis by impairing autophagic flux during obesity. [PDF]

Front Physiol
Huang D, Zou Y, Chan E, Kidd JM, Wu X, Zhang Y, Gehr TWB, Li N, Li PL, Li G.   +9 more
europepmc   +1 more source

SIRT6 Attenuates Angiotensin II-Induced Podocyte Cholesterol Accumulation and Injury via Negative Modulation of SREBP2.

Kidney Blood Press Res
Yang Y, Ma J, Chang D, Ma S, Xu L, Dang J.   +5 more
europepmc   +1 more source

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Zoning in on podocytes

Kidney International, 2022
Podocytes undergo defined morphologic changes during development, homeostasis, and aging, and on injury. Quantitative podometric assessments of podocyte endowment provide a powerful tool to interrogate glomerular health. Expanding this approach to a regional assessment demonstrates that the podocytes from cortical, subcortical, and juxtamedullary ...
Stuart J, Shankland, Oliver, Wessely
openaire   +2 more sources

Podocyte progenitors and ectopic podocytes

Nature Reviews Nephrology, 2013
Two types of parietal podocyte were previously described in the Bowman capsule: one characterized by coexpression of podocyte and parietal epithelial cell markers, the other characterized by expression of podocyte markers only. New research demonstrates that these populations represent podocyte progenitors and ectopic podocytes—distinct cell types with
Laura Lasagni, Paola Romagnani
openaire   +4 more sources

Roles of the podocyte in glomerular function

American Journal of Physiology - Renal Physiology, 2000
The podocyte is the most differentiated cell type in the glomerulum, which forms a crucial component of the glomerular filtration barrier. It has been assumed that podocyte foot processes counteract the elastic force of the glomerular basement membrane ...
H Pavenstädt
exaly   +2 more sources

The immune podocyte

Current Opinion in Rheumatology, 2019
Purpose of review Lupus nephritis (LN) is a serious manifestation of systemic lupus erythematosus and is characterized by proteinuria and renal failure. Proteinuria is a marker of poor prognosis and is attributed to podocyte loss and dysfunction. It is often debated whether these cells are innocent bystanders or
Rhea, Bhargava, George C, Tsokos
openaire   +2 more sources