Results 161 to 170 of about 50,846 (317)

UNI‐494 treatment improves measures of renal dysfunction and cardiac pathology in male rats receiving L‐NAME and angiotensin II

open access: yesPhysiological Reports, Volume 13, Issue 21, November 2025.
Abstract Mitochondrial dysfunction is essential in the pathophysiology of both cardiovascular disease (CVD) and chronic kidney disease (CKD). Nicorandil, a nicotinamide nitrate derivative, has been used for years as a cardioprotective agent. It binds to sulfonylurea receptors, activating mitochondrial ATP‐sensitive potassium channels (MitoKATP) and ...
Fiona Jing Min Ho   +9 more
wiley   +1 more source

Effect of the antiplatelet drug dilazep dihydrochloride on urinary podocytes in patients in the early stage of diabetic nephropathy. [PDF]

open access: bronze, 2000
Tsukasa Nakamura   +6 more
openalex   +1 more source

Developmental Hypoxia Enhances Kidney Organoid Complexity and Maturity

open access: yesAdvanced Science, Volume 12, Issue 40, October 27, 2025.
The current bottleneck in metanephric mesenchyme (MM)‐derived nephron organoid development is the absence of a connected network of collecting ducts (CD) derived from the ureteric bud (UB). To address this limitation, this study proposes a hypoxia‐based differentiation method that mimics the natural renal developmental environment, enabling the ...
Hyeonji Lim   +6 more
wiley   +1 more source

NAD(P)H oxidase activity in cultured human podocytes: Effects of adenosine triphosphate

open access: bronze, 1998
Stefan Greiber   +5 more
openalex   +1 more source

Tunneling Nanotube‐Mediated Transcellular Autophagy Alleviates Cadmium Induced Hepatocyte Injury

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
ROS accumulation is an important upstream signal for activating transcellular autophagy. Incomplete autophagy and TNT formation are necessary conditions for activating transcellular autophagy, and the disruption of the autophagic fusion mechanism is a trigger for activating transcellular autophagy.
Tao Wang   +13 more
wiley   +1 more source

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