Results 211 to 220 of about 68,048 (352)

[Podocyte dysfunction and proteinuria].

open access: yesNederlands tijdschrift voor geneeskunde, 2004
Podocytes play a central role in the pathogenesis of several glomerular diseases. In recent years, this has been revealed by molecular analysis of a number of rare hereditary renal diseases. Podocytes contain three domains: the domain bound to the glomerular basement membrane (GBM), the domain of the slit diaphragms and the apical domain.
Vogtländer, N.P.J.   +3 more
openaire   +3 more sources

Is loss of podocyte foot processes necessary for the induction of proteinuria? [PDF]

open access: bronze, 2005
S. Ananth Karumanchi   +2 more
openalex   +1 more source

Proteinuria After Kidney Transplantation

open access: yesPediatric Transplantation, Volume 29, Issue 8, December 2025.
ABSTRACT Proteinuria is a relatively frequent complication in both adults and children after kidney transplantation (40%–80%). It is usually mild and predominantly of tubular origin and is caused mainly by rejection, mTOR inhibitors, or hypertension; however, proteinuria could also be in the nephrotic range and of glomerular origin if caused by the ...
Tomas Seeman   +6 more
wiley   +1 more source

Evaluation of the role of evolutionary conserved polarity mechanisms in the establishment of podocyte architecture

open access: yes, 2014
Podozyten sind auf Grund ihrer Rolle in der Formierung und dem Erhalt der Schlitzmembran ein essentieller Bestandteil der glomerulären Filtrationsbarriere der Niere. Sowohl Formierung als auch Erhalt der Filtrationsbarriere ist abhängig von der korrekten
Djuric, I. (Ivona)
core  

The Impact of Complement Factor H‐Related Protein Gene Deletions on Kidney Transplantation

open access: yesScandinavian Journal of Immunology, Volume 102, Issue 6, December 2025.
In this study, we found that rs7542235 allele G tags a deletion of the CFHR1 gene. We also found that rs6677604 allele A tags a deletion of the whole CFHR3–1 locus. The plasma proteomics studies show that both variants are associated with an altered expression of FH/FHR proteins thus revealing a novel level of intricate regulation of the complement ...
Markkinen Salla   +6 more
wiley   +1 more source

Resistance to doxorubicin‐induced proteinuria and proteolytic activation of ENaC in 129S2/SvPas mice

open access: yesPhysiological Reports, Volume 13, Issue 23, December 2025.
Abstract Doxorubicin treatment of mice represents a convenient model to study the effects of proteinuria on proteolytic processing of the epithelial Na+ channel (ENaC) and urinary Na+ and fluid handling. Prior studies have shown enhanced ENaC γ subunit proteolysis and Na+ and fluid retention in 129S1/SvImJ mice treated with doxorubicin.
Evan C. Ray   +7 more
wiley   +1 more source

Podocyte-Specific VEGF-A Gain of Function Induces Nodular Glomerulosclerosis in eNOS Null Mice [PDF]

open access: bronze, 2014
Delma Verón   +5 more
openalex   +1 more source

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