Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review). [PDF]
Zhang P +6 more
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Qing-Re-Xiao-Zheng-yi-qi formula protects renal function by stabilizing lysosomal membranes and inhibiting NLRP3-inflammasome-mediated pyroptosis in diabetic kidney disease. [PDF]
Tian L +5 more
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The PLA2R Paradox: Seropositive Membranous Nephropathy With Negative Staining. [PDF]
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C3a/C3aR axis is involved in diabetic kidney injury by regulating podocyte mitophagy in diabetic nephropathy. [PDF]
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Therapeutic potential of ISG20 in attenuating podocyte injury via inhibition of ferroptosis. [PDF]
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CCL5 paradoxically regulates glomerular injury by skewing macrophage polarization. [PDF]
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Podocyte progenitors and ectopic podocytes
Nature Reviews Nephrology, 2013Two types of parietal podocyte were previously described in the Bowman capsule: one characterized by coexpression of podocyte and parietal epithelial cell markers, the other characterized by expression of podocyte markers only. New research demonstrates that these populations represent podocyte progenitors and ectopic podocytes—distinct cell types with
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Podocytes undergo defined morphologic changes during development, homeostasis, and aging, and on injury. Quantitative podometric assessments of podocyte endowment provide a powerful tool to interrogate glomerular health. Expanding this approach to a regional assessment demonstrates that the podocytes from cortical, subcortical, and juxtamedullary ...
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