Results 1 to 10 of about 13,097 (241)
Role of Podoplanin-Positive Cells in Cardiac Fibrosis and Angiogenesis After Ischemia [PDF]
Frontiers in Physiology, 2021 New insights into the cellular and extra-cellular composition of scar tissue after myocardial infarction (MI) have been identified. Recently, a heterogeneous podoplanin-expressing cell population has been associated with fibrogenic and inflammatory ...
Maria Cimini, Raj Kishore
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Molecular Therapy: Oncolytics, 2022 Glioblastoma is a devastating malignant brain tumor with a poor prognosis despite standard therapy. Podoplanin (PDPN), a type I transmembrane mucin-like glycoprotein that is overexpressed in various cancers, is a potential therapeutic target for the ...
Lushun Chalise +13 more
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Serum Podoplanin Levels as a Potential Biomarker for Diabetic Nephropathy Progression: A Cross-Sectional Study [PDF]
Diabetes, Metabolic Syndrome and ObesityFeng Huan,1 Xia Jiang2 1Public Health Medical Prevention Collaboration Department, First People’s Hospital, Nantong City, Jiangsu, 226014, People’s Republic of China; 2Department of Nephrology, Nantong Rehabilitation Hospital (Nantong Second People’s ...
Huan F, Jiang X
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Scientific Reports, 2022 This study aimed to investigate the spatial distribution and clinical significance of podoplanin expression in the metastatic lymph nodes of oropharyngeal squamous cell carcinomas (OPSCCs).
Hye Ran Lee +6 more
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Podoplanin is Responsible for the Distinct Blood and Lymphatic Capillaries [PDF]
Cellular and Molecular Bioengineering, 2022 Controlling the formation of blood and lymphatic vasculatures is crucial for engineered tissues. Although the lymphatic vessels originate from embryonic blood vessels, the two retain functional and physiological differences even as they develop in the ...
Donghyun Paul Jeong +3 more
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Near-Infrared Photoimmunotherapy Targeting Podoplanin-Expressing Cancer Cells and Cancer-Associated Fibroblasts. [PDF]
Molecular Cancer Therapeutics, 2022 Near-infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that utilizes an antibody-IRDye700DX (IR700) conjugate that binds to a target followed by the application of NIR light that results in dramatic changes in solubility of the conjugate ...
T. Kato +9 more
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Biomolecules, 2022 Our aim was to evaluate the expression of biomarkers, CD44v6, CD147, EGFR, p53, p63, p73, p16, and podoplanin in oral leukoplakias (OL) and to assess their potential for prediction of malignant transformation (MT).
Luís Monteiro +7 more
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The Role of Podoplanin in the Immune System and Inflammation
Journal of Inflammation Research, 2022 Zhiyuan Zhang,* Nan Zhang,* Jing Yu,* Wenting Xu, Jiameng Gao, Xin Lv, Zongmei Wen Department of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, People’s Republic of China*These ...
Zhang Z +6 more
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Podoplanin: Its roles and functions in neurological diseases and brain cancers
Frontiers in Pharmacology, 2022 Podoplanin is a small mucin-like glycoprotein involved in several physiological and pathological processes in the brain including development, angiogenesis, tumors, ischemic stroke and other neurological disorders. Podoplanin expression is upregulated in
Yi Wang +5 more
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Evaluation of podoplanin expression in vulvar squamous cell carcinoma and stromal fibroblasts and its prognostic implications [PDF]
Scientific ReportsAlthough the immunohistochemical expression of the transmembrane sialoglycoprotein podoplanin (D2-40) has been repeatedly reported as a factor of prognosis in various tumor entities—its potential prognostic relevance in squamous cell carcinomas of the ...
Gilbert Georg Klamminger +11 more
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