Results 1 to 10 of about 12,689 (186)

Differential expression of podoplanin in metastatic lymph node is associated with extranodal extension in oropharyngeal cancer

open access: yesScientific Reports, 2022
This study aimed to investigate the spatial distribution and clinical significance of podoplanin expression in the metastatic lymph nodes of oropharyngeal squamous cell carcinomas (OPSCCs).
Hye Ran Lee   +6 more
doaj   +2 more sources

Podoplanin Expression Independently and Jointly with Oral Epithelial Dysplasia Grade Acts as a Potential Biomarker of Malignant Transformation in Oral Leukoplakia

open access: yesBiomolecules, 2022
Our aim was to evaluate the expression of biomarkers, CD44v6, CD147, EGFR, p53, p63, p73, p16, and podoplanin in oral leukoplakias (OL) and to assess their potential for prediction of malignant transformation (MT).
Luís Monteiro   +7 more
doaj   +2 more sources

Role of Podoplanin-Positive Cells in Cardiac Fibrosis and Angiogenesis After Ischemia

open access: yesFrontiers in Physiology, 2021
New insights into the cellular and extra-cellular composition of scar tissue after myocardial infarction (MI) have been identified. Recently, a heterogeneous podoplanin-expressing cell population has been associated with fibrogenic and inflammatory ...
Maria Cimini, Raj Kishore
doaj   +2 more sources

The Role of Podoplanin in the Immune System and Inflammation

open access: yesJournal of Inflammation Research, 2022
Zhiyuan Zhang,* Nan Zhang,* Jing Yu,* Wenting Xu, Jiameng Gao, Xin Lv, Zongmei Wen Department of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, People’s Republic of China*These ...
Zhang Z   +6 more
doaj   +2 more sources

Podoplanin: Its roles and functions in neurological diseases and brain cancers

open access: yesFrontiers in Pharmacology, 2022
Podoplanin is a small mucin-like glycoprotein involved in several physiological and pathological processes in the brain including development, angiogenesis, tumors, ischemic stroke and other neurological disorders. Podoplanin expression is upregulated in
Yi Wang   +5 more
doaj   +2 more sources

Efficacy of cancer-specific anti-podoplanin CAR-T cells and oncolytic herpes virus G47Δ combination therapy against glioblastoma

open access: yesMolecular Therapy: Oncolytics, 2022
Glioblastoma is a devastating malignant brain tumor with a poor prognosis despite standard therapy. Podoplanin (PDPN), a type I transmembrane mucin-like glycoprotein that is overexpressed in various cancers, is a potential therapeutic target for the ...
Lushun Chalise   +13 more
doaj   +2 more sources

Evaluation of podoplanin expression in vulvar squamous cell carcinoma and stromal fibroblasts and its prognostic implications [PDF]

open access: yesScientific Reports
Although the immunohistochemical expression of the transmembrane sialoglycoprotein podoplanin (D2-40) has been repeatedly reported as a factor of prognosis in various tumor entities—its potential prognostic relevance in squamous cell carcinomas of the ...
Gilbert Georg Klamminger   +11 more
doaj   +2 more sources

Prognostic Value of Podoplanin in Various Tumors

open access: yesTechnology in Cancer Research & Treatment, 2021
Background: The prognostic significance of podoplanin (PDPN) in tumor cells for cancer patients’ survival remains controversial. Therefore, we performed this meta-analysis to clarify the relationship between the podoplanin-positive tumor cells and cancer
Xiaohang Wang PhD   +9 more
doaj   +2 more sources

Expression of podoplanin in oral premalignant and malignant lesions and its potential as a biomarker

open access: goldIndian Journal of Dental Research, 2014
Aim: To analyze and compare the expression of podoplanin in normal oral tissues, leukoplakia and oral squamous cell carcinoma (OSCC) and to predict its use as a biomarker. Materials and Methods: Ninety-two formalin fixed paraffin embedded tissue samples
J Logeswari   +4 more
doaj   +2 more sources

Elevated Serum Podoplanin Levels Correlate with Disease Severity and Inflammation in Ulcerative Colitis: A Cross-Sectional Study [PDF]

open access: yesJournal of Inflammation Research
Xiaogang Huang,1 Caifang Tang2 1Department of Gastroenterology, Sijing Hospital, Shanghai, 201601, People’s Republic of China; 2Department of Nursing, Sijing Hospital, Shanghai, 201601, People’s Republic of ChinaCorrespondence: Caifang Tang, Department ...
Huang X, Tang C
doaj   +2 more sources

Home - About - Disclaimer - Privacy