Results 31 to 40 of about 6,527,208 (145)

Structural Evaluation and Conformational Dynamics of ZNF141T474I Mutation Provoking Postaxial Polydactyly Type A

open access: yesBioengineering, 2022
Postaxial Polydactyly (PAP) is a congenital disorder of limb abnormalities characterized by posterior extra digits. Mutations in the N-terminal region of the Zinc finger protein 141 (ZNF141) gene were recently linked with PAP type A. Zinc finger proteins
Yasir Ali   +8 more
doaj   +1 more source

Versatile CRISPR/Cas9 Systems for Genome Editing in Ustilago maydis

open access: yesJournal of Fungi, 2021
The phytopathogenic smut fungus Ustilago maydis is a versatile model organism to study plant pathology, fungal genetics, and molecular cell biology. Here, we report several strategies to manipulate the genome of U.
Sarah-Maria Wege   +5 more
doaj   +1 more source

Genetic analysis of NS5B gene from bovine viral diarrhea virus-infected cattle in Central and East Java, Indonesia [PDF]

open access: yesVeterinary World, 2019
Background and Aim: A previous study divided Indonesian bovine viral diarrhea virus (BVDV)-1 into subgenotypes BVDV-1a to BVDV-1d based on the partial NS5B gene using strain Bega as reference for BVDV-1a. In fact, it is clustered into BVDV-1c with strain
S. H. Irianingsih   +5 more
doaj   +1 more source

A Simple, Improved Method for Scarless Genome Editing of Budding Yeast Using CRISPR-Cas9

open access: yesMethods and Protocols, 2022
Until recently, the favored method for making directed modifications to the budding yeast genome involved the introduction of a DNA template carrying the desired genetic changes along with a selectable marker, flanked by homology arms. This approach both
Rhiannon R. Aguilar   +2 more
doaj   +1 more source

QUANTITATIVE RHOA Gly17Val ALLELE-SPECIFIC POLYMERASE CHAIN REACTION AND T-CELL CLONALITY ANALYSIS IN ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA

open access: yesОнкогематология, 2018
Introduction. Аngioimmunoblastic T-cell lymphoma (AITL) is a T-cell lymphoma, characterized by abundant polymorphocellular infiltrate of lymph nodes with the small number of tumor CD4+ T-cells.
Yu. V. Sidorova   +11 more
doaj   +1 more source

Two Point Mutations on CYP51 Combined With Induced Expression of the Target Gene Appeared to Mediate Pyrisoxazole Resistance in Botrytis cinerea

open access: yesFrontiers in Microbiology, 2020
Botrytis cinerea is a destructive plant pathogenic ascomycete that causes serious pre- and post-harvest losses worldwide. The novel sterol 14α-demethylase inhibitor (DMI) pyrisoxazole was recently registered for the control of tomato gray mold caused by ...
Can Zhang   +7 more
doaj   +1 more source

Glyphosate-Resistant Goosegrass from Mississippi

open access: yesAgronomy, 2013
A suspected glyphosate-resistant goosegrass [Eleusine indica (L.) Gaertn.] population, found in Washington County, Mississippi, was studied to determine the level of resistance and whether the resistance was due to a point mutation, as was previously ...
Vijay K. Nandula   +2 more
doaj   +1 more source

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib.

open access: yesNew England Journal of Medicine, 2005
Mutations of the epidermal growth factor receptor (EGFR) gene have been identified in specimens from patients with non-small-cell lung cancer who have a response to anilinoquinazoline EGFR inhibitors.
Susumu S. Kobayashi   +9 more
semanticscholar   +1 more source

Resistance risk and molecular mechanism associated with resistance to picoxystrobin in Colletotrichum truncatum and Colletotrichum gloeosporioides

open access: yesJournal of Integrative Agriculture, 2023
Anthracnose, caused by Colletotrichum truncatum and C. gloeosporioides, is amongst the most serious diseases of soybean in China. Picoxystrobin, a quinone outside inhibitor fungicide, is commonly used for the control of anthracnose.
Niu-niu SHI   +4 more
doaj  

Mutations Associated with Imatinib Mesylate Resistance - Review

open access: yesFolia Medica, 2018
Chronic myeloid leukemia (CML) arises from the fusion of the BCR and the ABL1 genes. The BCR gene (chromosome 22q11.2) and the ABL1 gene (chromosome 9q34) fuse together due to reciprocal chromosome translocation forming the Philadelphia chromosome (Ph ...
Linev Alexandar J.   +5 more
doaj   +1 more source

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