Results 41 to 50 of about 1,268,660 (340)

QUANTITATIVE RHOA Gly17Val ALLELE-SPECIFIC POLYMERASE CHAIN REACTION AND T-CELL CLONALITY ANALYSIS IN ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA

Онкогематология, 2018
Introduction. Аngioimmunoblastic T-cell lymphoma (AITL) is a T-cell lymphoma, characterized by abundant polymorphocellular infiltrate of lymph nodes with the small number of tumor CD4+ T-cells.
Yu. V. Sidorova, N. G. Chernova, I. A. Yakutik, S. Yu. Smirnova, N. V. Ryzhikova, E. E. Nikulina, M. Yu. Aleksenko, M. N. Sinitsyna, A. M. Kovrigina, T. N. Moiseeva, E. E. Zvonkov, A. B. Sudarikov   +11 more
doaj   +1 more source

Mutations in the Second Alternative Oxidase Gene: A New Approach to Group Aspergillus niger Strains

Journal of Fungi, 2023
Alternative oxidase is a terminal oxidase in the branched mitochondrial electron transport chain of most fungi including Aspergillus niger (subgenus Circumdati, section Nigri). A second, paralogous aox gene (aoxB) is extant in some A.
Michel Flipphi, Alexandra Márton, Vivien Bíró, Norbert Ág, Erzsébet Sándor, Erzsébet Fekete, Levente Karaffa   +6 more
doaj   +1 more source

On Exceptional Times for generalized Fleming-Viot Processes with Mutations

, 2013
If $\mathbf Y$ is a standard Fleming-Viot process with constant mutation rate (in the infinitely many sites model) then it is well known that for each $t>0$ the measure $\mathbf Y_t$ is purely atomic with infinitely many atoms.
B Schmuland, DA Dawson, DA Dawson, Donnelly, EB Dynkin, J Berestycki, J Bertoin, J Bertoin, J Bertoin, J Jacod, J Lamperti, J Pitman, J Pitman, LA Shepp, M Birkner, M Birkner, M Birkner, N Berestyck, N Ikeda, N Konno, P Donnelly, SN Ethier, SN Ethier, T Duquesne, TG Kurtz, WH Fleming, Z Fu, Z Li, Z Li   +28 more
core   +2 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Site-directed mutagenesis of cysteine to serine residues affects heparin binding and mitogenicity in fibroblast growth factor 4 produced in Escherichia coli

Biotechnology & Biotechnological Equipment, 2019
The binding activity to heparan sulphate is crucial for the mitogenic activity of fibroblast growth factor 4 (FGF4) in developing mammalian embryos. There are two conserved cysteine residues in FGF family proteins, Cys-84 and Cys-151 in mouse FGF4, and ...
Yuki Kumagai, Takahiro Kikuchi, Asumi Nonaka, Misuzu Hiraide, Suguru Sato, Mizuki Sakuraoka, Akira Sasaki, Masayuki Kobayashi   +7 more
doaj   +1 more source

DNMT3A GENE POINT MUTATIONS DETECTION IN ACUTE MYELOID LEUKEMIA PATIENTS USING SEQUENCING TECHNIQUE

Бюллетень сибирской медицины, 2015
Aim: to estimate the frequency of DNMT3A gene exons 18–26 point mutations in acute myeloid leukemia (AML) patients (pts) using target automatic sequencing technique.Material and Methods.
A. V. Vinogradov, A. V. Rezaykin, A. G. Sergeev   +2 more
doaj   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Novel mutation in PLP1 gene in an individual with Pelizaeus-Merzbacher disease (PMD) using whole exome sequencing [PDF]

Journal of Epigenetics
Background: Pelizaeus-Merzbacher disease (PMD) is a rare X-linked genetic disorder affecting the central nervous system. This disease is associated with abnormalities of the white matter of the brain and spinal cord.
Nagham Mahdi Hamid Abdollah, Narges Javadzadeh   +1 more
doaj   +1 more source

Phylogeny, Antifungal Susceptibility, and Point Mutations of SQLE Gene in Major Pathogenic Dermatophytes Isolated From Clinical Dermatophytosis

Frontiers in Cellular and Infection Microbiology, 2022
Drug resistance is one of the major challenges to skin fungal infections, especially in tropical and subtropical infections caused by dermatophytes. This study aimed to determine the antifungal susceptibility of clinically dermatophytes and evaluate ...
Nasrin Pashootan, Masoomeh Shams-Ghahfarokhi, Arash Chaichi Nusrati, Zahra Salehi, Mehdi Asmar, Mehdi Razzaghi-Abyaneh   +5 more
doaj   +1 more source

The Role of CaMK-II in the Development of Leukemia/Lymphoma in Danio Rerio [PDF]

, 2017
Acute lymphocytic leukemia (ALL) is a blood disorder characterized by aberrant proliferation of immature lymphocytes. ALL is the most common cancer in children and can result from external influences, such as radiation, or internal influences, such as ...
Mohammadi, Daniel
core   +1 more source