Testing of disease-resistance of pokeweed antiviral protein gene (PacPAP) in transgenic cucumber (Cucumis sativus) [PDF]
Transformation of pokeweed antiviral protein gene (PAP) into plants was shown to improve plant resistance to several viruses or fungi pathogens with no much negative effect on plant growth.
Cao, B +6 more
core +2 more sources
Pokeweed antiviral protein (PAP) is a protein known to inactivate eukaryotic ribosomes by an unknown enzymatic action and inhibit the production of mammalian viruses in tissue culture. This protein was subjected to a variety of chemical modifications to determine their effects upon ribosomal inactivation, antiviral action, and cytotoxicity.
Irvin, James D., Aron, Gary M.
openaire +2 more sources
Expression of a pokeweed antiviral protein in Escherichia coli and its characterization [PDF]
Two expression vectors were constructed to produce a putative mature α‐pokeweed antiviral protein (α‐PAP) in Escherichia coli with its NH2‐ and COOH‐terminal extrapeptides excised. One was for its intracellular expression with a methionine at its NH2‐terminal. The other was for its secretion using an ompA signal peptide. The former product was purified
Kataoka, Jiro +6 more
openaire +2 more sources
Comparative in vitro imunotoxicology of acyclovir and other antiviral agents [PDF]
In vitro lymphocyte blastogenic responses to the commonly employed mitogens phytohemagglutinin, pokeweed, and concanavalin A were evaluated when acyclovir, adenine arabinoside, cytosine arabinoside, and idoxuridine were added to the culture materials ...
Steele, Russell W. +2 more
core
Pharmaceutical Crops: An Overview [PDF]
Pharmaceutical crops is an ambiguous term used by biologists and chemists for different categories of plants. We define pharmaceutical crops as those cultivated species that are used for extraction or preparation of therapeutic substances such as active ...
Antoun, Mikhail +5 more
core +1 more source
The hepatotoxicity of aqueous methanol extract and fractionated-methanol extract of Phytolacca americana in male rat using perfusion method [PDF]
چکیده: زمینه و هدف: سرخاب با نام علمی Phytolacca americana گیاه بومی ایالت های مختلف آمریکا است که به صورت گسترده مصرف می شود. برگ های پخته آن به سالاد مادر بزرگ (Grandmother salad) معروف است و در ایران در نوار ساحلی و جنگل های شمال به وفور یافت می شود ...
Karami, Mohammad. +3 more
core
Characterization of Defense-Associated Gene Expression in Phytolacca Americana Using Novel Transcriptomic and Genomic Resources [PDF]
Phytolacca americana (pokeweed) is a non-model plant with agriculturally relevant characteristics, being a heavy metal hyperaccumulator resistant to virus infection.
Neller, Kira Catherine Maxine
core
Plant Ribosomal Proteins, RPL12 and RPL19, Play a Role in Nonhost Disease Resistance against Bacterial Pathogens [PDF]
Characterizing the molecular mechanism involved in nonhost disease resistance is important to understand the adaptations of plant-pathogen interactions.
Keri Wang +4 more
core +2 more sources
Transcriptional Regulation of Pokeweed Antiviral Protein [PDF]
Phytolacca americana (American pokeweed) expresses pokeweed antiviral protein (PAP), a ribosome-inactivating protein (RIP) thought to function in defence.
Diaz, Camille Anne
core
The chemical stability of abasic RNA compared to abasic DNA [PDF]
We describe the synthesis of an abasic RNA phosphoramidite carrying a photocleavable 1-(2-nitrophenyl)ethyl (NPE) group at the anomeric center and a triisopropylsilyloxymethyl (TOM) group as 2′-O-protecting group together with the analogous DNA and the 2′
Küpfer, Pascal A. +1 more
core

