Results 101 to 110 of about 1,915,574 (342)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Public knowledge about polar regions increases while concerns remain unchanged [PDF]

, 2012
The authors of this brief conduct the first comparative analysis of the polar questions that were part of the National Opinion Research Center\u27s 2006 and 2010 General Social Survey.
Cutler, Matthew J., Hamilton, Lawrence C., Schaefer, Andrew P.   +2 more
core   +1 more source

Polarizing Persuasion

Games and Economic Behavior
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Axel Anderson, Nikoloz Pkhakadze
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Polar auxin transport controls suspensor fate [PDF]

, 2008
Emma Larsson, Folke Sitbon, Sara von Arnold   +2 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

De "Wuata Wuara" a "Raza de bronce"

Nueva Revista de Filología Hispánica, 1987
En este número no se incluyeron resúmenes ni palabras clave.    
Antonio Cornejo Polar
doaj   +1 more source

Mixed Methods in Decision-Making Through Polar Coordinate Technique: Differences by Gender on Beach Handball Specialist [PDF]

, 2019
Juan Antonio Vázquez-Diz, Juan P. Morillo-Baro, Rafael E. Reigal, Verónica Morales‐Sánchez, António Hernández-Mendo   +4 more
openalex   +1 more source

CHINA AND NIGERIA RELATIONS IN A MULTI-POLAR WORLD

, 2023
Anthony Chukwuemeke NWOKOLOBIA, Francis Ayegbunam IKENGA   +1 more
openalex   +1 more source

Polarization considerations [PDF]

SPIE Proceedings, 1998
As light passes through a optical system the reflections and refractions will in general change the polarization state of the light. If we assume that all of the materials in the thin film coating and substrate are isotropic and homogeneous then calculating the amount of "instrumental” polarization is a relatively straight forward task.
openaire   +1 more source