Results 11 to 20 of about 46,021 (228)

Enterovirus infections in children. [PDF]

Pediatr Investig
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Chen X, Guo L, Lei X, Zhao L, Hei M, Shen J, Yin J, Li F, Deng J, Liu G, Zhang Y, Xie Z.   +11 more
europepmc   +2 more sources

Protecting investments in polio eradication: the past, present and future of surveillance for acute flaccid paralysis. [PDF]

, 2004
In September 2003 a WHO consultation group on vaccine-derived polioviruses (VDPV) concluded that in order to prevent future generations of paralytic polio after interruption of transmission of wild poliovirus, the use of trivalent oral polio vaccine (OPV)
D. L. HEYMANN, E. M. DE GOURVILLE, Heymann, DL, R. B. AYLWARD, Aylward, RB, De Gourville, EM   +5 more
core   +1 more source

Immunity levels to poliovirus in Lao children and adults before the vaccine-derived poliovirus outbreak: A retrospective study [PDF]

, 2018
In 2015, several provinces in Lao People's Democratic Republic (Lao PDR) experienced a vaccine-derived poliovirus outbreak. This survey was conducted (i) to evaluate the vaccination coverage in different settings and cohorts using the seroprevalence of ...
Nouanthong, Phonethipsavanh, Nanthavong, Naphavanh, Samountry, Bounthome, Xeuatvongsa, Anonh, Sayasinh, Kong, Jutavijittum, Prapan, Khampanisong, Phonepaseuth, Hübschen, Judith M, Black, Antony P., Diedrich, Sabine, Pauly, Maude, Muller, Claude P.   +11 more
core   +1 more source

The effect of maternal poliovirus antibodies on the immune responses of infants to poliovirus vaccines

BMC Infectious Diseases, 2020
Background Maternal poliovirus antibodies could provide passive immunity to the newborns from poliovirus infection during their first few months of life, but they may impair the immune responses of infants to the poliovirus vaccine as well. In our study,
Siyue Jia, Rong Tang, Guifan Li, Yuemei Hu, Qi Liang   +4 more
doaj   +1 more source

Recombination in enteroviruses is a biphasic replicative process involving the generation of greater-than genome length 'imprecise' intermediates [PDF]

, 2014
Recombination in enteroviruses provides an evolutionary mechanism for acquiring extensive regions of novel sequence, is suggested to have a role in genotype diversity and is known to have been key to the emergence of novel neuropathogenic variants of ...
David J Evans, Woodman, Andrew, Andrew Woodman, Kym Lowry (222718), Jonathan Cook (3435386), Andrew Woodman (577477), Cook, Jonathan, Cook, Jonathan P., David J. Evans (208308), Lowry, Kym, David J. Evans, Evans, David J., Kym Lowry, Jonathan Cook   +13 more
core   +1 more source

Theiler's murine encephalomyelitis protein 2C and its effect on membrane trafficking [PDF]

, 2008
Picornaviruses replicate in association with cytoplasmic membranes of infected cells. Poliovirus 2C and 2BC play an important role in the formation of membranous vesicles, and induce dramatic changes in membrane trafficking.
Moës, Elien
core   +2 more sources

Update on Pakistan Polio Eradication Initiative

Journal of Shalamar Medical & Dental College, 2022
The global polio eradication initiative (GPEI) was established in 1988 as a result of the declaration of commitment by the World Health Assembly. In Pakistan, National Emergency Action Plan [NEAP] coined the strategies under government directives to ...
Maryam Riaz Tarar
doaj   +1 more source

Effects of maternal antibodies in infants on the immunogenicity and safety of inactivated polio vaccine in infants

Human Vaccines & Immunotherapeutics, 2022
The presence of maternal poliovirus antibodies may interfere with the immune response to inactivated polio vaccine (IPV), and its influence on the safety of vaccination is not yet understood.
Shuyu Gao, Mingwei Wei, Kai Chu, Jingxin Li, Fengcai Zhu   +4 more
doaj   +1 more source

Poliovirus biology [PDF]

Structure, 1996
Poliomyelitis has been largely controlled by the use of attenuated live vaccine strains. The molecular basis of attenuation is beginning to be understood, but the interactions between the virus and its human host remain mysterious.
openaire   +2 more sources

Postabsorption neutralization of poliovirus [PDF]

Journal of Virology, 1993
Nineteen neutralizing murine monoclonal antibodies against poliovirus type 1, including representatives reacting with each of the antigenic sites on the virion, were tested for their abilities to neutralize the virus either before or after attachment to susceptible cells.
Vrijsen, Raphael, Mosser, A., Boeye, Albert   +2 more
openaire   +3 more sources