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The oral poliovirus vaccine (OPV) has been the mainstay of polio eradication, especially in low-income countries, and its use has eliminated wild poliovirus type 2.
Muhammad Atif Habib +8 more
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This Policy Statement was retired January 2015. Despite marked progress in global polio eradication, the threat of polio importation into the United States remains; therefore, all children should be protected against the disease. The standard schedule for poliovirus immunization remains 4 doses of inactivated poliovirus vaccine at 2, 4 ...
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Enteroviruses are among the most common viruses infecting humans and can cause diverse clinical syndromes ranging from minor febrile illness to severe and potentially fatal diseases.
Maël Bessaud +18 more
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Background Maternal poliovirus antibodies could provide passive immunity to the newborns from poliovirus infection during their first few months of life, but they may impair the immune responses of infants to the poliovirus vaccine as well. In our study,
Siyue Jia +4 more
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Poliomyelitis has been largely controlled by the use of attenuated live vaccine strains. The molecular basis of attenuation is beginning to be understood, but the interactions between the virus and its human host remain mysterious.
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Update on Pakistan Polio Eradication Initiative
The global polio eradication initiative (GPEI) was established in 1988 as a result of the declaration of commitment by the World Health Assembly. In Pakistan, National Emergency Action Plan [NEAP] coined the strategies under government directives to ...
Maryam Riaz Tarar
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The presence of maternal poliovirus antibodies may interfere with the immune response to inactivated polio vaccine (IPV), and its influence on the safety of vaccination is not yet understood.
Shuyu Gao +4 more
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Postabsorption neutralization of poliovirus [PDF]
Nineteen neutralizing murine monoclonal antibodies against poliovirus type 1, including representatives reacting with each of the antigenic sites on the virion, were tested for their abilities to neutralize the virus either before or after attachment to susceptible cells.
Vrijsen, Raphael +2 more
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Objective: In response to an outbreak of circulating vaccine-derived poliovirus (cVDPV) type 2 in the Philippines in 2019–2020, several rounds of supplementary immunization activities using the monovalent type 2 oral poliovirus vaccine (OPV) were ...
SweetC B Alipon +12 more
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Poliovirus as an antigen [PDF]
Calculations have been carried out which indicate that poliovirus vaccine contains sufficient antigen to account for the observed antibody response.
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