Results 11 to 20 of about 88,319 (314)

Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame. [PDF]

Expert Review of Vaccines, 2015
The polio eradication endgame aims to bring transmission of all polioviruses to a halt. To achieve this aim, it is essential to block viral replication in individuals via induction of a robust mucosal immune response. Although it has long been recognized
Anis E, Davis DC, Edward PK Parker, Ghendon YZ, Glezen WP, Glezen WP, Herremans MM, Herremans TM, Hovi T, Kathleen M O’Reilly, Margarita Pons-Salort, Marine WM, Natalie A Molodecky, Nicholas C Grassly, Ogra PL, Wehrle PF, WHO Collaborative Study Group on Oral and Inactivated Poliovirus Vaccines   +16 more
core   +4 more sources

THERMOSENSITIVITY OF POLIOVIRUS [PDF]

Journal of Bacteriology, 1963
Wallis, Craig(Baylor University College of Medicine, Houston, Tex.)and Joseph L. Melnick. Thermosensitivity of poliovirus. J. Bacteriol.86:499–504. 1963.—Polioviruses are thermosensitive agents, although thermoresistant strains have been obtained and reported in the literature. Such resistant strains can be developed by exposure of the virus to cystine
Craig Wallis, Joseph L. Melnick
openalex   +3 more sources

Public Health Response to a Case of Paralytic Poliomyelitis in an Unvaccinated Person and Detection of Poliovirus in Wastewater — New York, June–August 2022

MMWR. Morbidity and mortality weekly report, 2022
On July 18, 2022, the New York State Department of Health (NYSDOH) notified CDC of detection of poliovirus type 2 in stool specimens from an unvaccinated immunocompetent young adult from Rockland County, New York, who was experiencing acute flaccid ...
R. Link-Gelles, E. Lutterloh, Patricia Schnabel Ruppert, P. B. Backenson, K. St. George, E. Rosenberg, Bridget J. Anderson, M. Fuschino, Michael Popowich, Chitra Punjabi, Maria Souto, Kevin T McKay, S. Rulli, T. Insaf, D. Hill, Jessica Kumar, I. Gelman, J. Jorba, T. Ng, N. Gerloff, N. Masters, A. López, K. Dooling, Shannon K. Stokley, S. Kidd, M. Oberste, J. Routh, Hanen Belgasmi, Barrett Brister, James Edward Bullows, C. Burns, Christina J. Castro, Janine Cory, N. Dybdahl-Sissoko, B. Emery, Randall English, Ann D. Frolov, Halle Getachew, Elizabeth Henderson, Alexandra Hess, K. Mason, Jeffrey W Mercante, S. Miles, Hongmei Liu, Rachel L. Marine, Nehalraza Momin, Hong Pang, D. Perry, Shannon L. Rogers, Brandon D. Short, Hong Sun, F. Tobolowsky, E. Yee, S. Hughes, E. Omoregie, J. Rosen, J. Zucker, M. Alazawi, U. Bauer, A. Godinez, Brianna Hanson, E. Heslin, James McDonald, N. K. Mita-Mendoza, Megan D Meldrum, D. Neigel, Robin Suitor, D. Larsen, C. Egan, Nicola Faraci, G. S. Feumba, T. Gray, D. Lamson, Jennifer Laplante, K. McDonough, Natalie Migliore, Amruta Moghe, Simon Ogbamikael, Jonathan Plitnick, R. Ramani, Lindsey Rickerman, Erik Rist, Lynsey Schoultz, Matthew Shudt, Julie Krauchuk, Eric Medina, J. Lawler, H. Boss, E. Barca, Danish H. Ghazali, Tarini Goyal, Sean J.P. Marinelli, J. Roberts, Grace B. Russo, K. Thakur, Vivian Q. Yang   +95 more
semanticscholar   +1 more source

Update on Vaccine-Derived Poliovirus Outbreaks — Worldwide, January 2020–June 2021

MMWR. Morbidity and mortality weekly report, 2021
As of May 1, 2016, use of oral poliovirus vaccine (OPV) type 2 for routine and supplementary immunization activities ceased after a synchronized global switch from trivalent OPV (tOPV; containing Sabin strain types 1, 2, and 3) to bivalent OPV (bOPV ...
M. Alleman, J. Jorba, Elizabeth Henderson, O. Diop, S. Shaukat, M. Traore, E. Wiesen, S. Wassilak, C. Burns   +8 more
semanticscholar   +1 more source

Mucosal immunity to poliovirus

Mucosal Immunology, 2021
A cornerstone of the global initiative to eradicate polio is the widespread use of live and inactivated poliovirus vaccines in extensive public health campaigns designed to prevent the development of paralytic disease and interrupt transmission of the ...
R. Connor, E. Brickley, Wendy F. Wieland-Alter, M. Ackerman, J. Weiner, J. Modlin, A. Bandyopadhyay, Peter F. Wright   +7 more
semanticscholar   +1 more source

Evolving epidemiology of poliovirus serotype 2 following withdrawal of the serotype 2 oral poliovirus vaccine

Science, 2020
A public health catch-22 In 2016, the serotype 2 component of the oral poliovirus vaccine given to children was withdrawn. This measure was taken to prevent vaccine-associated disease outbreaks caused by mutation in the live attenuated vaccine.
Grace R. Macklin, K. O'Reilly, N. Grassly, W. Edmunds, O. Mach, R. Krishnan, Arend Voorman, J. Vertefeuille, J. Abdelwahab, N. Gumede, A. Goel, S. Sosler, J. Sever, A. Bandyopadhyay, M. Pallansch, R. Nandy, P. Mkanda, O. Diop, R. Sutter   +18 more
semanticscholar   +1 more source

Interaction of the poliovirus receptor with poliovirus [PDF]

Proceedings of the National Academy of Sciences, 2000
The structure of the extracellular, three-domain poliovirus receptor (CD155) complexed with poliovirus (serotype 1) has been determined to 22-Å resolution by means of cryo-electron microscopy and three-dimensional image-reconstruction techniques. Density corresponding to the receptor was isolated in a difference electron density map and fitted with ...
He, Yongning, Bowman, Valorie D., Mueller, Steffen, Bator, Carol M., Bella, Jordi, Peng, Xiaozhong, Baker, Timothy S., Wimmer, Eckard, Kuhn, Richard J., Rossmann, Michael G.   +9 more
openaire   +3 more sources

Development of a new oral poliovirus vaccine for the eradication end game using codon deoptimization

npj Vaccines, 2020
Enormous progress has been made in global efforts to eradicate poliovirus, using live-attenuated Sabin oral poliovirus vaccine (OPV). However, as the incidence of disease due to wild poliovirus has declined, vaccine-derived poliovirus (VDPV) has emerged ...
Jennifer L. Konopka-Anstadt, R. Campagnoli, A. Vincent, J. Shaw, Lingxiu Wei, N. Wynn, S. Smithee, E. Bujáki, Ming Te Yeh, M. Laassri, T. Zagorodnyaya, A. Weiner, K. Chumakov, R. Andino, A. Macadam, O. Kew, C. Burns   +16 more
semanticscholar   +1 more source

Update on Vaccine-Derived Poliovirus Outbreaks — Worldwide, July 2019–February 2020

MMWR. Morbidity and mortality weekly report, 2020
Circulating vaccine-derived polioviruses (cVDPVs) can emerge in areas with low poliovirus immunity and cause outbreaks* of paralytic polio (1-5). Among the three types of wild poliovirus, type 2 was declared eradicated in 2015 (1,2). The use of trivalent
M. Alleman, J. Jorba, Sharon A. Greene, O. Diop, Jane Iber, G. Tallis, A. Goel, E. Wiesen, S. Wassilak, C. Burns   +9 more
semanticscholar   +1 more source

Rapid and Sensitive Direct Detection and Identification of Poliovirus from Stool and Environmental Surveillance Samples by Use of Nanopore Sequencing

Journal of Clinical Microbiology, 2020
Global poliovirus surveillance involves virus isolation from stool and environmental samples, intratypic differential (ITD) by PCR, and sequencing of the VP1 region to distinguish vaccine (Sabin), vaccine-derived, and wild-type polioviruses and to ensure
Alexander G. Shaw, M. Majumdar, C. Troman, Á. O'toole, B. Benny, D. Abraham, I. Praharaj, G. Kang, S. Sharif, M. Alam, S. Shaukat, M. Angez, A. Khurshid, Nayab Mahmood, Y. Arshad, L. Rehman, G. Mujtaba, Ribqa Akthar, M. Salman, D. Klapsa, Yara Hajarha, H. Asghar, A. Bandyopadhyay, A. Rambaut, Javier Martin, N. Grassly   +25 more
semanticscholar   +1 more source