Results 81 to 90 of about 218,086 (209)

Guideline for the Diagnosis and Management of Heritable IFNAR1 Deficiency in Oceania

Journal of Paediatrics and Child Health, Volume 62, Issue 7, Page 1113-1120, July 2026.
ABSTRACT Autosomal recessive interferon alpha and beta receptor subunit 1 (IFNAR1) deficiency is a rare and heritable inborn error of immunity (IEI) predisposing individuals to severe and life‐threatening viral infections. It is more common in people of Western Polynesian ancestry, with estimates of around one in six thousand live births affected, due ...
Cecilia Verryt, Paul Gray, Peter McNaughton, Jane Peake, Melanie Wong, George Aho, Emma Best, Maia Brewerton, Flora Lutui, Litara Esera Tulifau, Rebecca Qin, Satupa‘itea Viali, Petine White, Andrew Wood, See‐Tarn Woon, Theresa Cole, Alberto Pinzon Charry, Kuang‐Chih Hsiao   +17 more
wiley   +1 more source

Characterization of environmental and clinical surveillance inputs to support prospective integrated modeling of the polio endgame.

PLOS Global Public Health
National, regional, and global poliovirus surveillance needs continue to expand and evolve. The 1988 global resolution to eradicate polio necessitated the creation and support for a global poliovirus surveillance system able to identify poliovirus ...
Kamran Badizadegan, Kimberly M Thompson
doaj   +1 more source

Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy

Aggregate, Volume 7, Issue 6, June 2026.
Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao, Dong Wang, Lei Wang, Hongkai Zhang, Yue Sun, Dan Ding   +5 more
wiley   +1 more source

Integrating acute flaccid paralysis surveillance, environmental surveillance and vaccination strategies to prevent poliovirus re-emergence in Nigeria: a narrative review

Discover Public Health
Background Although wild poliovirus (WPV) transmission has been interrupted in Nigeria, the post-certification era continues to present significant risks of poliovirus re-emergence, driven predominantly by circulating vaccine-derived poliovirus type 2 ...
Eric O. Nwaze, Mathew Ashikeni
doaj   +1 more source

Human Circulating Antibody-Producing B Cell as a Predictive Measure of Mucosal Immunity to Poliovirus.

PLoS ONE, 2016
BackgroundThe "gold standard" for assessing mucosal immunity after vaccination with poliovirus vaccines consists in measuring virus excretion in stool after challenge with oral poliovirus vaccine (OPV).
Ayan Dey, Natalie A Molodecky, Harish Verma, Prashant Sharma, Jae Seung Yang, Giulietta Saletti, Mohammad Ahmad, Sunil K Bahl, Thomas F Wierzba, Ranjan K Nandy, Jagadish M Deshpande, Roland W Sutter, Cecil Czerkinsky   +12 more
doaj   +1 more source

Plant-made poliovirus vaccines - Safe alternatives for global vaccination. [PDF]

Front Plant Sci, 2022
Bolaños-Martínez OC, Strasser R.
europepmc   +1 more source

Antiviral Development for the Polio Endgame: Current Progress and Future Directions

Pathogens
As the world is approaching the eradication of wild poliovirus serotype 1, the last of the three wild types, the question of how to maintain a polio-free world becomes imminent.
Hang Xie, Eric E. Rhoden, Hong-Mei Liu, Folake Ogunsemowo, Bernardo A. Mainou, Rachel M. Burke, Cara C. Burns   +6 more
doaj   +1 more source

Outbreak response strategies with type 2-containing oral poliovirus vaccines. [PDF]

Vaccine, 2023
Kalkowska DA, Wassilak SGF, Pallansch MA, Burns CC, Wiesen E, Durry E, Badizadegan K, Thompson KM.   +7 more
europepmc   +1 more source

Evaluation of poliovirus vaccines for pestivirus contamination : non-specific amplification of poliovirus sequences by pan-pestivirus primers

, 2002
Two lots of polyvalent live vaccines for human use against poliovirus were tested by reverse transcriptase (RT) and nested PCR for the presence of contaminating pestivirus RNA.
Angelika Braun, Büttner, Mathias, Mathias Büttner, Panuccio, A., Giangaspero, M., Carlo Zanotto, Alfonso Panuccio, Massimo Giangaspero, Elli, V., M. Buttner, A. Braun, Carlo De Giuli Morghen, C. Zanotto, ELLI, VERONICA, A. Panuccio, A. Radaelli, Braun, A., Zanotto, C., Radaelli, A., Antonia Radaelli, C. De Giuli Morghen, M. Giangaspero, Veronica Elli, Morghen, C.D.   +23 more
core   +1 more source

Poliovirus circulation in the WHO European region, 2015–2022: a review of data from WHO's three core poliovirus surveillance systemsResearch in context

The Lancet Regional Health. Europe
Summary: Background: The Global Polio Eradication Initiative (GPEI) has drastically reduced the global incidence of poliomyelitis since its launch in 1988 thanks to effective vaccines and strong global surveillance systems.
Thea K. Fischer, Caroline K. Johannesen, Kimberley S.M. Benschop, Natasa Berginc, Eugene V. Saxentoff, Shahin Huseynov, José E. Hagan, Heli Harvala   +7 more
doaj   +1 more source