Results 61 to 70 of about 218,086 (209)
Background/Objectives: Hematopoietic stem cell transplantation (HSCT) can potentially cure hematological malignancies; however, post-transplant patients have a high risk of infection owing to their immunocompromised status. Vaccination against pathogens,
Taiichiro Kobayashi +9 more
doaj +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald +6 more
wiley +1 more source
Determination of Factors Affecting Bivalent (Type 1 and 3) Stability of Oral Poliomyelitis Vaccine
Background and objectives: After using of trivalent oral poliovirus vaccine (OPV) for a long time in Iran, in recent years, due to the eradication of type 2 of poliovirus, a bivalent vaccine containing types 1 and 3 is used.
Sina Soleimani
doaj
Acute flaccid paralysis (AFP) is a rare side effect of the oral polio vaccine but can be associated with outbreaks and permanent disability in patients harboring circulating vaccine-derived polioviruses (cVDPVs).
Mary Bridget Nanteza +11 more
doaj +1 more source
Unmasking the Influence of Viral Micro‐RNAs on Host Immunity
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton +1 more
wiley +1 more source
Theiler's murine encephalomyelitis protein 2C and its effect on membrane trafficking [PDF]
Picornaviruses replicate in association with cytoplasmic membranes of infected cells. Poliovirus 2C and 2BC play an important role in the formation of membranous vesicles, and induce dramatic changes in membrane trafficking.
Moës, Elien
core +2 more sources
For enteroviruses such as poliovirus (PV), empty capsids, which are antigenically indistinguishable from mature virions, are produced naturally during viral infection.
Lee Sherry +6 more
doaj +1 more source
The evolving role of immunotherapy in ovarian cancer
Abstract Ovarian cancer remains a major cause of gynecologic cancer mortality; and, although immune checkpoint inhibitors have transformed treatment in other solid tumors, their activity in ovarian cancer has been limited by tumor heterogeneity, an immunosuppressive tumor microenvironment, and the lack of robust predictive biomarkers.
Ana Carolina Veneziani +2 more
wiley +1 more source
Improving cellular cancer vaccines [PDF]
Immunization with cancer cells is of great demand in anti-cancer therapy. However, current cellular vaccines are inefficient and there are questions regarding their overall safety. We report a simple and straightforward approach for improving of cellular
Petr Lokhov
core

