Results 11 to 20 of about 8,665 (215)
Analysis of codon usage and nucleotide composition bias in polioviruses [PDF]
Background Poliovirus, the causative agent of poliomyelitis, is a human enterovirus and a member of the family of Picornaviridae and among the most rapidly evolving viruses known.
Jie Zhang +8 more
core +3 more sources
Poliovirus intrahost evolution is required to overcome tissue-specific innate immune responses. [PDF]
RNA viruses, such as poliovirus, have a great evolutionary capacity, allowing them to quickly adapt and overcome challenges encountered during infection.
Andino, Raul +6 more
core +4 more sources
Surveillance for acute flaccid paralysis syndrome (AFP) in children under 15 is the backbone of the Global Polio Eradication Initiative. Laboratory examination of stool samples from AFP cases allows the detection of, along with polioviruses, a variety of
Olga E. Ivanova +15 more
doaj +1 more source
Enteroviruses (EVs) are associated with a wide spectrum of diseases involving various organs. Our aim was to give a historical overview of the genesis of clinical sample processing for EVs in the Slovak Republic (SR) during the 1958–2020 period, within ...
Renata Kissova +6 more
doaj +1 more source
Has wild poliovirus been eliminated from Nigeria? [PDF]
Wild poliovirus type 3 (WPV3) has not been seen anywhere since the last case of WPV3-associated paralysis in Nigeria in November 2012. At the time of writing, the most recent case of wild poliovirus type 1 (WPV1) in Nigeria occurred in July 2014, and ...
Famulare, Michael
core +7 more sources
Is it time to switch to a formulation other than the live attenuated poliovirus vaccine to prevent poliomyelitis? [PDF]
The polioviruses (PVs) are mainly transmitted by direct contact with an infected person through the fecal-oral route and respiratory secretions (or more rarely via contaminated water or food) and have a primary tropism for the gut.
Devaux CA +4 more
europepmc +2 more sources
Introduction: This study assessed the seroprevalence against all three polioviruses among the last cohort of infants aged 6-11 months who received tOPV before the tOPV-bOPV switch and had an opportunity to receive a full dose of inactivated poliovirus ...
Mohammad Ahmad +11 more
doaj +1 more source
Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame. [PDF]
The polio eradication endgame aims to bring transmission of all polioviruses to a halt. To achieve this aim, it is essential to block viral replication in individuals via induction of a robust mucosal immune response. Although it has long been recognized
Anis E +16 more
core +3 more sources
Experience of application of IgY-technology for laboratory diagnostics of viral infections
Introduction. The well-known advantages of class Y antibodies (IgY) from egg yolks of immunized hens in comparison with class G antibodies (IgG) of laboratory animals traditionally used in laboratory diagnosis of infectious diseases determine the stable ...
A. P. Ivanov +2 more
doaj +1 more source
The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG +6 more
core +1 more source

