Peribulbar poloxamer for ocular drug delivery [PDF]
Acta Ophthalmologica, 2008 Abstract.Purpose: The use of biopolymers in peribulbar injection for controlled drug delivery provides alternative options to eyedrops and intravitreal or surgical methods. Polymerizable biopolymers are especially likely to have a role because of their particular properties.
Katja, Vehanen +3 more
openaire +2 more sources
Effect of Poloxamer 407 on serum VLDL, LDL and HDL levels of rabbits
National Journal of Physiology, Pharmacy and Pharmacology, 2014 Background: Poloxamer 407 is used in parenteral formulations as solubilizing and wetting agent for traditional, low-molecular-weight organic drug molecules and as stabilizing agent for proteins and polypeptide drugs.
Harish Govind Naik +5 more
doaj +1 more source
Drugs for preventing red blood cell dehydration in people with sickle cell disease. [PDF]
, 2016 BACKGROUND: Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and may block blood vessels leading to acute painful crises and other complications.
Ballas, Samir K., Nagalla, Srikanth
core +2 more sources
Mechanical, Rheological and Release Behaviors of a Poloxamer 407/ Poloxamer 188/Carbopol 940 Thermosensitive Composite Hydrogel [PDF]
Molecules, 2013 The aims of this study were to prepare a thermosensitive composite hydrogel (TCH) by mixing 24% (w/v) poloxamer 407 (P407), 16% (w/v) poloxamer 188 (P188) and 0.1% (w/v) carbopol 940 (C940), and to determine the effect of natural borneol/ (2-hydroxypropyl)-β-cyclodextrin (NB/HP-β-CD) inclusion complex on the phase transition temperature, mechanical ...
Jianyu Su +5 more
openaire +3 more sources
Evaluation of 25% Poloxamer As a Slow Release Carrier for Morphine in a Rat Model
Frontiers in Veterinary Science, 2018 The objectives of this study were to evaluate poloxamer as a slow release carrier for morphine (M) and potential tissue irritation after subcutaneous poloxamer–morphine (PM) injection in a rat model.
Nurul H. Sulimai +7 more
doaj +1 more source
Analysis of Compounded Pharmaceutical Products to Teach the Importance of Quality in an Applied Pharmaceutics Laboratory Course [PDF]
, 2014 Objective. To assess the effectiveness of a product-analysis laboratory exercise in teaching students the importance of quality in pharmaceutical compounding. Design.
Almoazen +9 more
core +2 more sources
Antitumoral activity of micellar solutions containing allyl isothiocyanate: an in vitro study
Ars Pharmaceutica, 2021 Introduction: Several natural products exhibit promising antineoplastic activity against bladder cancer cells, including allyl isothiocyanate (AITC).
Tamires Cunha Almeida +5 more
doaj +1 more source
Evaluating Poloxamers as Agents for Acceleration of Skeletal Muscle Membrane Repair [PDF]
, 2018 Sarcolemmal membrane fragility is a major contributor to the pathology of various muscular dystrophies, including Duchenne Muscular Dystrophy (DMD). DMD is a fatal X- linked genetic disorder resulting from a loss of the dystrophin protein.
Rose, Aubrey
core +1 more source
Development and Study of Antibacterial In situ Coatings for Processing Implants
Разработка и регистрация лекарственных средств, 2023 Introduction. Periprosthetic infections are a major problem in orthopedic surgery. The most optimal way to influence the bacterial film is to suppress the early stages of its formation.
E. O. Bakhrushina +5 more
doaj +1 more source
Formulation development of a carrageenan based delivery system for buccal drug delivery using ibuprofen as a model drug [PDF]
, 2011 Solvent cast films are used as oral strips with potential to adhere to the mucosal surface, hydrate and deliver drugs across the buccal membrane. The objective of this study was the formulation development of bioadhesive films with optimum drug loading
Antonijevic, Milan D. +3 more
core +1 more source