Results 41 to 50 of about 22,356 (221)
Molecules, 2017 Emodin is a component in a Chinese herb, Rheum officinale Baill, traditionally used for diabetes and anticancer. Its poor solubility is one of the major challenges to pharmaceutical scientists.
Eunmi Ban +6 more
doaj +1 more source
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]
, 2020 Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core +1 more source
Evaluating antibiotics for use in medicine using a poloxamer biofilm model [PDF]
, 2007 Background Wound infections, due to biofilms, are a constant problem because of their recalcitrant nature towards antibiotics. Appropriate antibiotic selection for the treatment of these biofilm infections is important.
Clutterbuck Abi L +3 more
core +2 more sources
Pharmaceutics, 2022 Abiraterone acetate is a prodrug of abiraterone used in combination with prednisone as a standard therapeutic strategy for hormone-resistant prostate cancer (mCRPC).
Yuanfen Liu +5 more
doaj +1 more source
Antibiotics, 2021 Candida albicans is a common overgrowth in people wearing dentures. Long-term use of antifungal chemicals carries a risk of toxic side effects. This study focused on the edible Piper betle extract because of its safety.
Siriporn Okonogi +4 more
doaj +1 more source
Controlled release ibuprofen-poloxamer gel for epidural use - A pharmacokinetic study using microdialysis in pigs [PDF]
, 2016 In order to avoid the risks of sideeffects of epidural local anesthetics and opioids, the use of nonsteroidal anti-inflammatory drugs (NSAIDs) epidurally would be an interesting option of analgesic therapy. The fairly short duration of action of spinally
Bernards, Christopher M. +2 more
core +1 more source
Concentration-Dependent Viscoelasticity of Poloxamer-Shelled Microbubbles
Langmuir, 2022 The oscillation of shelled microbubbles during exposure to ultrasound is influenced by the mechanical properties of the shell components. The oscillation behavior of bubbles coated with various phospholipids and other amphiphiles has been studied. However, there have been few investigations of how the adsorption conditions of the shell molecules relate
Tabata, Hiraku +4 more
openaire +2 more sources
Preparation and characterization of spray-dried valsartan-loaded Eudragit® E PO solid dispersion microparticles [PDF]
, 2016 The purpose of this study was to develop the immediate release stomach-specific spray-dried formulation of valsartan (VAL) using Eudragit® E PO (EPO) as the carrier for enhancing dissolution rate in a gastric environment.
Taylor +21 more
core +6 more sources
FORMULATION AND CHARACTERIZATION OF POLOXAMER 407 (R): THERMOREVERSIBLE GEL CONTAINING POLYMERIC MICROPARTICLES AND HYALURONIC ACID [PDF]
, 2013 The influence of the composition and preparation method on the sol-gel transition temperature (Tsol-gel) and rheological response of poloxamer-based formulations was determined.
Dimer, FA +5 more
core +3 more sources
Injectable Poloxamer Hydrogels for Local Cancer Therapy
Gels, 2023 The widespread push to invest in local cancer therapies comes from the need to overcome the limitations of systemic treatment options. In contrast to intravenous administration, local treatments using intratumoral or peritumoral injections are independent of tumor vasculature and allow high concentrations of therapeutic agents to reach the tumor site ...
Ana Camila Marques +3 more
openaire +3 more sources