Results 1 to 10 of about 3,509 (173)

Block copolypeptide nanoparticles for the delivery of ocular therapeutics [PDF]

, 2014
Self-assembling block copolypeptides were prepared by sequential ring-opening polymerization of N-carboxyanhydride (NCA) derivatives of γ-benzyl-L-glutamic acid and ε-carbobenzyloxy-L-lysine, followed by selective deprotection of the benzyl glutamate ...
Andrés-Guerrero, Vanessa, Caballo Gonzalez, Maria, Cameron, Neil R., Dose, Anica, Groenen, Alexander J.J., Hehir, Sarah, Herrero Vanrell, Rocio, Stukenkemper, Timo   +7 more
core   +1 more source

The Enrichment of Whey Protein Isolate Hydrogels with Poly-γ-Glutamic Acid Promotes the Proliferation and Osteogenic Differentiation of Preosteoblasts

Gels, 2023
Osseous disease accounts for over half of chronic pathologies, but there is a limited supply of autografts, the gold standard; hence, there is a demand for new synthetic biomaterials.
Daniel K. Baines, Varvara Platania, Nikoleta N. Tavernaraki, Mattia Parati, Karen Wright, Iza Radecka, Maria Chatzinikolaidou, Timothy E. L. Douglas   +7 more
doaj   +1 more source

Polymeric nanogels as vaccine delivery systems [PDF]

, 2013
Polymeric nanogels find a relevant field of application in the formulation of a new generation of therapeutic and preventive vaccines, aiming at the fine-tuned modulation of the immune response.
Ferreira, Sílvia A., Gama, F. M., Vilanova, Manuel   +2 more
core   +1 more source

Improving survival of probiotic bacteria using bacterial poly-γ-glutamic acid [PDF]

, 2014
A major hurdle in producing a useful probiotic food product is bacterial survival during storage and ingestion. The aim of this study was to test the effect of γ-PGA immobilisation on the survival of probiotic bacteria when stored in acidic fruit juice ...
Bartlett, T., Bhat, A. R., Charalampopoulos, Dimitris, Hill, D., Irorere, V. U., Kedia, G., Nualkaekul, S., Radecka, I.   +7 more
core   +1 more source

Poly-γ-Glutamic Acid Attenuates Angiogenesis and Inflammation in Experimental Colitis

Mediators of Inflammation, 2013
Poly-γ-glutamic acid (γ-PGA), naturally secreted from various strains of Bacillus, has anti-inflammatory activity. In inflammatory bowel disease (IBD), inflammation is promoted and sustained by angiogenesis; however, the role played by γ-PGA in this ...
Munkhtugs Davaatseren, Jin-Taek Hwang, Jae Ho Park, Myung-Sunny Kim, Shuaiyu Wang, Mi Jeong Sung   +5 more
doaj   +1 more source

Poly-γ-glutamic acid: production, properties and applications [PDF]

, 2015
University of Wolverhampton ...
Adetoro Ogunleye, Aditya Bhat, Ben-Zur, Bhat, Bhunia, Bodnár, Bovarnick, Candela, Cao, Choi, Craig Williams, Cromwick, David Hill, Graciela, Hanby, Ho, Ho, Inbaraj, Ivanovics, Ivanovics, Iza Radecka, Kada, Li, Mabrouk, Makino, McLean, Mesnage, Rehm, Sakai, Shih, Shyu, Sung, Thorne, Thorne, Tomcsik, Tsutomu, Uotani, Victor U. Irorere, Weber, Xu, Yasuzawa, Yokoi, Zwartouw   +42 more
core   +1 more source

Vaccine delivery using nanoparticles [PDF]

, 2016
This is the final version of the article. Available from the publisher via the DOI in this record.Vaccination has had a major impact on the control of infectious diseases.
Gregory, AE, Titball, R, Williamson, D
core   +1 more source

Production of poly-γ-glutamic acid by a thermotolerant glutamate-independent strain and comparative analysis of the glutamate dependent difference

AMB Express, 2017
Poly-γ-glutamic acid (γ-PGA) is a promising microbial polymer with wide applications in industry, agriculture and medicine. In this study, a novel glutamate-independent γ-PGA producing strain with thermotolerant characteristics was isolated and ...
Wei Zeng, Guiguang Chen, Ye Guo, Bin Zhang, Mengna Dong, Yange Wu, Jun Wang, Zhiqun Che, Zhiqun Liang   +8 more
doaj   +1 more source

The era of bioengineering: how will this affect the next generation of cancer immunotherapy? [PDF]

, 2017
Immunotherapy consists of activating the patient's immune system to fight cancer and has the great potential of preventing future relapses thanks to immunological memory.
Berti, C., Graciotti, M., Kandalaft, L., Klok, H.A.   +3 more
core   +2 more sources

Synthesis of Hydrogels Made of Poly-γ-Glutamic Acid (γ-PGA) for Potential Applications as Probiotic-Delivery Vehicles

Applied Sciences, 2020
Numerous hydrogels made of poly-γ-glutamic acid (γ-PGA) and various cross-linkers have been explored, but only limited data on hydrogels made of γ-PGA and poly(ethylene glycol) (PEG) are available.
Iwona Kwiecień, Daria Niewolik, Anabel Itohowo Ekere, Abhishek Gupta, Izabela Radecka   +4 more
doaj   +1 more source