Bacillus subtilis sups. chungkookjang produces a higher molecular mass poly-γ-glutamic acid (γ-PGA). Recently, previous studies have demonstrated immune stimulation and an antitumor effect of the high molecular mass γ-PGA using various mouse models ...
Seo Byoung-Joo +8 more
doaj +1 more source
HARVESTING OF FRESHWATER MICROALGAE BY BACTERIAL BIOFLOCCULANT [PDF]
随着世界对食品、饲料、生物燃料和化工产品需求的日益增长,微藻成为了被广泛接受的最具有前景的原材料之一。然而,微藻细胞个体微小,培养密度低,藻体难以高效收集,影响了微藻产品的生产和商业化。本研究从经济和环保的角度出发,建立了一种使用生物絮凝剂絮凝收集藻体的方法。方法使用地衣芽孢杆菌CGMCC2876生产的聚谷氨酸作为生物絮凝剂,絮凝并收集淡水藻体,同时使用zeta电位测定和DLVO经典理论对絮凝过程进行了分析研究,并对絮凝操作的可放大性和原位操作的可行性进行了实验评估。此外 ...
THEONESTE NDIKUBWIMANA
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Photothermal-modulated drug delivery and magnetic relaxation based on collagen/poly(γ-glutamic acid) hydrogel [PDF]
Injectable and stimuli-responsive hydrogels have attracted attention in molecular imaging and drug delivery because encapsulated diagnostic or therapeutic components in the hydrogel can be used to image or change the microenvironment of the injection ...
Ahreum Kim +7 more
core +2 more sources
Complexation and conformation of lead ion with poly-γ-glutamic acid in soluble state.
Complexation of microbial polymer in soluble state could impact the solubility, mobility, and bioavailability of heavy metals in the environment. The complexation of a bacterial exopolymer, poly-γ-glutamic acid (γ-PGA), with Pb2+ was studied using the ...
Lingling Wang +5 more
doaj +1 more source
Microbial synthesis of poly-γ-glutamic acid (γ-PGA) with fulvic acid powder, the waste from yeast molasses fermentation. [PDF]
Li Y, Wang J, Liu N, Ke L, Zhao X, Qi G.
europepmc +1 more source
Cost-competitive γ-PGA production from low costs feedstock using an engineered Bacillus subtilis lab strain [PDF]
Poly-γ-glutamic acid (γ-PGA) represents one of the most promising biomaterial naturally secreted by microorganisms mainly belonging to the Bacillales order.
CALVIO, CINZIA +3 more
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Purification and Applications of poly-γ-glutamic acid from Bacillus licheniformis [PDF]
聚谷氨酸(γ-PGA),是一种全天然、多功能、生物可降解的生物高分子材料,具有水溶性、可食性、环境友好性等特征。本研究利用实验室自筛所得的地衣芽孢杆菌CGMCC2876,对其合成γ-PGA进行分离纯化,进而探索其相关应用。 以地衣芽孢杆菌CGMCC2876发酵液为原料,经过去除菌体和有机溶剂沉淀,获得纯度为60.7%的γ-PGA粗提物,其产量为28.6g•L-1;之后通过阴离子树脂交换层析和凝胶柱交换层析,进一步进行产物纯化,获得纯度为93.8%的γ-PGA终产物,其产量为4.79g ...
叶宏
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Electrofermentation increases concentration of poly γ‐glutamic acid in Bacillus subtilis biofilms
Fluctuations in redox conditions in bioprocesses can alter the end‐products, reduce their concentration, and lengthen the process time. Electrofermentation enables rapid metabolic modulation of biosynthesis and allows control of redox imbalances in ...
Alina Adilkhanova +9 more
doaj +1 more source
Recent advances on biocompatible and biodegradable nanoparticles as gene carriers [PDF]
Introduction: Gene therapy mainly depends on the use of appropriate delivery vehicles with no induction of immune responses and toxicity. The limitations of viral gene carriers such as induction of immunogenicity, random integration in the genome of ...
Alibakhshi, Abbas. +5 more
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Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies [PDF]
Poly-γ-glutamate (γ-PGA) is a natural polymer composed by glutamic acid residues, synthesized by the pgs operon of Bacillus subtilis. γ-PGA has a wide range of applications as food, cosmetic and pharmaceutical additive.
Arthur Zebre +6 more
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