Results 261 to 270 of about 547,441 (316)
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European Journal of Biochemistry, 1968
Some optical and thermodynamic properties of the double helical form of the alternating copolymer poly(A‐U) and the two stranded complex of poly A and poly U are compared. It is shown that their thermal difference spectra are closely similar when that of the latter complex is corrected for the hypochromicity of the poly A formed on denaturation ...
E G, Richards, H, Simpkins
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Some optical and thermodynamic properties of the double helical form of the alternating copolymer poly(A‐U) and the two stranded complex of poly A and poly U are compared. It is shown that their thermal difference spectra are closely similar when that of the latter complex is corrected for the hypochromicity of the poly A formed on denaturation ...
E G, Richards, H, Simpkins
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Association of Poly(A) and Poly(U) Polymerases with Cytoplasmic Ribosomes
European Journal of Biochemistry, 1978Cytoplasmic ribosomes of Ehrlich ascites tumour cells were isolated under conditions where ribonuclease contamination is minimized. These ribosomes displayed poly(A) and poly(U) polymerase activity with [3H]ATP or [3H]UTP as substrates, while incorporation of [3H]GTP or [3H]CTP was not observed.
G I, Milchev, A A, Hadjiolov
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Inhibition of Entry of HIV into Cells by Poly(A)·Poly(U)
AIDS Research and Human Retroviruses, 1993Polyadenylic-polyuridylic acid referred to as poly (A)·poly(U), is a synthetic double-stranded RNA that has been shown to manifest both antitumoral and immunodulatory activities. Previously, we have reported that poly(A)·poly(U) inhibits HIV infection in cell cultures. Here we provide direct evidence to demonstrate that the inhibitory action of poly(A)·
B, Krust, C, Callebaut, A G, Hovanessian
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Poly (A) and Poly (U) in Poliovirus Double Stranded RNA
Nature New Biology, 1973Poliovirus double stranded RNA (the “replicative form”) contains poly (A) at the 3′-end of the plus (genome-like) strand which is longer than poly (A) found in polio virion RNA. Digestion with 3′-exonuclease, hybridization to labelled poly (A) or poly (U) and affinity chromatography reveal that the minus strand contains 3′-terminal poly (U).
Y, Yogo, E, Wimmer
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Molecular Biology Reports, 2014
Interaction of the 9-O-N-aryl/arylalkyl amino carbonyl methyl substituted analogs of the anticancer isoquinoline alkaloid berberine with RNA triplex, poly(U)-poly(A) · poly(U) has been studied in comparison to the duplex poly(A)-poly(U), using multiple biophysical techniques.
Anirban, Basu +2 more
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Interaction of the 9-O-N-aryl/arylalkyl amino carbonyl methyl substituted analogs of the anticancer isoquinoline alkaloid berberine with RNA triplex, poly(U)-poly(A) · poly(U) has been studied in comparison to the duplex poly(A)-poly(U), using multiple biophysical techniques.
Anirban, Basu +2 more
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The Journal of Biochemistry, 1987
The formation of the triple helix of poly(A).poly(U).poly(U) was studied by using antibodies specific to poly(A).poly(U).poly(U). the 10-11 base chain length for oligo(A) and the 20-30 base chain length for oligo(U) may be the minimum sizes required to maintain a stable triple helix. Double-stranded poly(A).poly(U) which was the core of triple-stranded
Y, Kitagawa, E, Okuhara
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The formation of the triple helix of poly(A).poly(U).poly(U) was studied by using antibodies specific to poly(A).poly(U).poly(U). the 10-11 base chain length for oligo(A) and the 20-30 base chain length for oligo(U) may be the minimum sizes required to maintain a stable triple helix. Double-stranded poly(A).poly(U) which was the core of triple-stranded
Y, Kitagawa, E, Okuhara
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Journal of Inorganic Biochemistry, 2015
Two new Ru(II) complexes with 1,8-naphthalimide group, [Ru(phen)2(pnip)](2+) (Ru1; phen=1,10-phenanthroline, pnip=2-[N-(p-phenyl)-1,8-napthalimide]imidazo[4',5'-f][1,10]phenanthroline) and [Ru(bpy)2(pnip)](2+) (Ru2; bpy=2,2'-bipyridine), have been synthesized and characterized. The interactions of Ru1 and Ru2 with the triplex RNA poly(U)•poly(A)*poly(U)
Jia, Li +4 more
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Two new Ru(II) complexes with 1,8-naphthalimide group, [Ru(phen)2(pnip)](2+) (Ru1; phen=1,10-phenanthroline, pnip=2-[N-(p-phenyl)-1,8-napthalimide]imidazo[4',5'-f][1,10]phenanthroline) and [Ru(bpy)2(pnip)](2+) (Ru2; bpy=2,2'-bipyridine), have been synthesized and characterized. The interactions of Ru1 and Ru2 with the triplex RNA poly(U)•poly(A)*poly(U)
Jia, Li +4 more
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Biopolymers, 1972
AbstractWe prepared helices with noncomplementary bases by N1‐oxidation of poly A, followed by reaction with poly U. Mixing curves indicate that doubly and triply helical structures form, with only the unmodified adenines involved in base pair formation.
T R, Fink, D M, Crothers
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AbstractWe prepared helices with noncomplementary bases by N1‐oxidation of poly A, followed by reaction with poly U. Mixing curves indicate that doubly and triply helical structures form, with only the unmodified adenines involved in base pair formation.
T R, Fink, D M, Crothers
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Suppression of hydrate and dimer formation in ultraviolet-irradiated poly (A + U) relative to poly U
Journal of Molecular Biology, 1966Abstract [ 32 P]Poly U and poly (A + U), containing a 1:1 mixture of poly A and [ 32 P]poly U, were irradiated at 280 mμ to study the influence of secondary structure on photoproduct formation in the uracil residues. Samples were removed as a function of exposure, hydrolyzed to completion with RNase, and chromatographed to give U, H ‡ , DU and DH ...
M, Pearson, H E, Johns
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Radiolysis of Poly(U) in Oxygenated Solution
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1986Aqueous N2O/O2-saturated solutions of poly(U) were irradiated at 0 degrees C and the release of unaltered uracil determined. Immediately after irradiation G(uracil release) was 1.5 which increased to a value of 5.3 +/- 0.3 upon heating to 95 degrees C. Thereby all of the organic hydroperoxides (G = 6.8 +/- 0.7) and some of the hydrogen peroxide (G = 1 ...
D J, Deeble, C, von Sonntag
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