Results 101 to 110 of about 24,007,230 (395)

Strategies for Regulating the Release Kinetics of Bioactive Compounds from Biopolymeric Hydrogels

Gels
Bioactive compounds are widely recognized for their ability to enhance health and prevent diseases due to their various biological activities. However, these compounds are very sensitive to environmental factors, which can reduce their solubility ...
Mizanur Rahman, Shahla Teimouri, Poly Rani Roy, António Raposo, Hmidan A. Alturki, Stefan Kasapis   +5 more
doaj   +1 more source

Soft nanotechnology: the potential of polyelectrolyte multilayers against E. coli adhesion to surfaces

Arhiv za Higijenu Rada i Toksikologiju, 2020
Preventing bacterial attachment to surfaces is the most efficient approach to controlling biofilm proliferation. The aim of this study was to compare anti-adhesion potentials of 5 and 50 mmol/L polyelectrolyte multilayers of poly(allylamine hydrochloride)
Fink Rok, Oder Martina, Jukić Jasmina, Cindro Nikola, Požar Josip   +4 more
doaj   +1 more source

APASdb: a database describing alternative poly(A) sites and selection of heterogeneous cleavage sites downstream of poly(A) signals

Nucleic Acids Res., 2014
Increasing amounts of genes have been shown to utilize alternative polyadenylation (APA) 3′-processing sites depending on the cell and tissue type and/or physiological and pathological conditions at the time of processing, and the construction of genome ...
Leiming You, Jiexin Wu, Yuchao Feng, Yonggui Fu, Yanan Guo, Liyuan Long, Hui Zhang, Yi Luan, P. Tian, Liangfu Chen, Guangrui Huang, Shengfeng Huang, Yuxin Li, Jie Li, Chengyong Chen, Yaqing Zhang, Shangwu Chen, A. Xu   +17 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Poly(A) tail dynamics, non-adenine incorporation and alternative polyadenylation shape the host transcriptome in COVID-19 pathogenesis

Scientific Reports
The COVID-19 pandemic has had a profound global impact since its emergence in late 2019. Characterized by a wide spectrum of clinical manifestations, COVID-19 has necessitated extensive research into the host-pathogen interactions that drive disease ...
Mateusz A. Maździarz, Katarzyna Krawczyk, Ewa Lepiarczyk, Łukasz Paukszto, Karol G. Makowczenko, Beata Moczulska, Piotr Iwanowicz, Piotr Kocbach, Krzysztof Nosek, Jakub Sawicki, Leszek Gromadziński, Marta Majewska   +11 more
doaj   +1 more source

Efficient Method for Molecular Characterization of the 5′ and 3′ Ends of the Dengue Virus Genome

Viruses, 2020
Dengue is a mosquito-borne disease that is of major importance in public health. Although it has been extensively studied at the molecular level, sequencing of the 5′ and 3′ ends of the untranslated regions (UTR) commonly requires specific approaches for
Alicia Rosales-Munar, Diego Alejandro Alvarez-Diaz, Katherine Laiton-Donato, Dioselina Peláez-Carvajal, Jose A. Usme-Ciro   +4 more
doaj   +1 more source

A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly(A) tail length

RNA: A publication of the RNA Society, 2014
This paper examines the function of the mammalian protein ZC3H14, which is a zinc finger polyadenosine binding protein that may be orthologous to the yeast protein Nab2.
Seth M. Kelly, Sara W. Leung, ChangHui Pak, A. Banerjee, K. Moberg, A. Corbett   +5 more
semanticscholar   +1 more source

Solvent resistant thermoplastic aromatic poly(imidesulfone) and process for preparing same [PDF]

, 1983
A process for preparing a thermoplastic poly(imidesulfone) is disclosed. This resulting material has thermoplastic properties which are generally associated with polysulfones but not polyimides, and solvent resistance which is generally associated with ...
St.clair, T. L., Yamaki, D. A.
core   +1 more source

Poly-MTO, {(CH_3)_{0.92} Re O_3}_\infty, a Conducting Two-Dimensional Organometallic Oxide [PDF]

, 2005
Polymeric methyltrioxorhenium, {(CH_{3})_{0.92}ReO_{3}}_{\infty} (poly-MTO), is the first member of a new class of organometallic hybrids which adopts the structural pattern and physical properties of classical perovskites in two dimensions (2D).
B. L. Altshuler, C. C. Tsuei, C. Helbig, C. Helbig, E.-W. Scheidt, F. Mayr, G. Eickerling, H.-A. Krug von Nidda, J. F. Gibson, J. Mink, J. T. Szymanski, P. Kiprof, P. Schwab, R. Herrmann, R. Miller, R. Miller, V. Eyert, W. A. Herrmann, W. Scherer   +18 more
core   +4 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source