Results 81 to 90 of about 115,568,697 (304)

Acoustical investigation of poly(dA).poly(dT), poly[d(A-T)].poly[d(A-T)], poly(A) . poly(U) and DNA hydration in dilute aqueous solutions [PDF]

Nucleic Acids Research, 1989
Apparent molar adiabatic compressibilities and apparent molar volumes of poly[d(A-T)].poly[d(A-T)], poly(dA).poly(dT), DNA and poly(A).poly(U) in aqueous solutions were determined at 1 degree C. The change of concentration increment of the ultrasonic velocity upon replacing counter ion Cs+ by the Mg2+ ion was also determined for these polymers.
V A, Buckin, B I, Kankiya, A P, Sarvazyan, H, Uedaira   +3 more
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Poly(A) tail dynamics, non-adenine incorporation and alternative polyadenylation shape the host transcriptome in COVID-19 pathogenesis

Scientific Reports
The COVID-19 pandemic has had a profound global impact since its emergence in late 2019. Characterized by a wide spectrum of clinical manifestations, COVID-19 has necessitated extensive research into the host-pathogen interactions that drive disease ...
Mateusz A. Maździarz, Katarzyna Krawczyk, Ewa Lepiarczyk, Łukasz Paukszto, Karol G. Makowczenko, Beata Moczulska, Piotr Iwanowicz, Piotr Kocbach, Krzysztof Nosek, Jakub Sawicki, Leszek Gromadziński, Marta Majewska   +11 more
doaj   +1 more source

Strategies for Regulating the Release Kinetics of Bioactive Compounds from Biopolymeric Hydrogels

Gels
Bioactive compounds are widely recognized for their ability to enhance health and prevent diseases due to their various biological activities. However, these compounds are very sensitive to environmental factors, which can reduce their solubility ...
Mizanur Rahman, Shahla Teimouri, Poly Rani Roy, António Raposo, Hmidan A. Alturki, Stefan Kasapis   +5 more
doaj   +1 more source

Efficient Method for Molecular Characterization of the 5′ and 3′ Ends of the Dengue Virus Genome

Viruses, 2020
Dengue is a mosquito-borne disease that is of major importance in public health. Although it has been extensively studied at the molecular level, sequencing of the 5′ and 3′ ends of the untranslated regions (UTR) commonly requires specific approaches for
Alicia Rosales-Munar, Diego Alejandro Alvarez-Diaz, Katherine Laiton-Donato, Dioselina Peláez-Carvajal, Jose A. Usme-Ciro   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Synthesis of Optically Active Poly(diphenylacetylene)s Using Polymer Reactions and an Evaluation of Their Chiral Recognition Abilities as Chiral Stationary Phases for HPLC

Molecules, 2016
A series of optically active poly(diphenylacetylene) derivatives bearing a chiral substituent (poly-2S) or chiral and achiral substituents (poly-(2Sx-co-31−x)) on all of their pendant phenyl rings were synthesized by the reaction of poly(bis(4 ...
Katsuhiro Maeda, Miyuki Maruta, Yuki Sakai, Tomoyuki Ikai, Shigeyoshi Kanoh   +4 more
doaj   +1 more source

Soft nanotechnology: the potential of polyelectrolyte multilayers against E. coli adhesion to surfaces

Arhiv za Higijenu Rada i Toksikologiju, 2020
Preventing bacterial attachment to surfaces is the most efficient approach to controlling biofilm proliferation. The aim of this study was to compare anti-adhesion potentials of 5 and 50 mmol/L polyelectrolyte multilayers of poly(allylamine hydrochloride)
Fink Rok, Oder Martina, Jukić Jasmina, Cindro Nikola, Požar Josip   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source