Results 91 to 100 of about 1,999,235 (294)
ANALYSIS OF HEALTH SERVICES MAXIMUM SUPPLY IN HOSPITAL SURABAYA
JPH RECODE (Journal of Public Health Research and Community Health Development), 2019 The importance of a health service in calculating the maximum supply is to ensure efficiency and effectiveness. To achieve efficiency and effectiveness it is important to pay attention to the combination of Human Resources and other resources ...
Novia Dewi Putri Ayuningtyas
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Efficient Method for Molecular Characterization of the 5′ and 3′ Ends of the Dengue Virus Genome
Viruses, 2020 Dengue is a mosquito-borne disease that is of major importance in public health. Although it has been extensively studied at the molecular level, sequencing of the 5′ and 3′ ends of the untranslated regions (UTR) commonly requires specific approaches for
Alicia Rosales-Munar +4 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
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FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
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DPAC: A Tool for Differential Poly(A)–Cluster Usage from Poly(A)–Targeted RNAseq Data
G3: Genes, Genomes, Genetics, 2019 Poly(A)-tail targeted RNAseq approaches, such as 3′READS, PAS-Seq and Poly(A)-ClickSeq, are becoming popular alternatives to random-primed RNAseq to focus sequencing reads just to the 3′ ends of polyadenylated RNAs to identify poly(A)-sites and ...
Andrew Routh
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Polyimides prepared from 3,5-diamino benzo trifluoride [PDF]
, 1993 High performance, thermooxidatively stable polyimides are prepared by reacting aromatic diamines with pendant trifluoromethyl groups and dianhydrides in an amide solvent to form a poly(amic acid), followed by cyclizing the poly(amic acid) to form the ...
Gerber, Margaret K. +3 more
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FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
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International Journal of Nanomedicine, 2008 Ye Sun1, Yuzhao Tang1, Maoquan Chu2, Shuxian Song1, Yanfei Xin31School of Life Science and Technology, Shanghai Jiaotong University, Shanghai, China; 2Institute of Life Science and Technology, Tongji University, Shanghai, China; 3School of Pharmacy ...
Ye Sun +4 more
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