Exchange reactions of poly(arylene ether ketone) dithioketals with aliphatic diols: formation and deprotection of poly(arylene ether ketal)s [PDF]
, 2017 The dithioketal derivatives of industrially important, semi-crystalline poly(arylene ether ketone)s undergo facile exchange with aliphatic diols in the presence of N-bromo-succinimide to give a range of novel poly(arylene ether ketal)s.
Colquhoun, Howard +2 more
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eLife, 2019 The Ccr4-Not complex removes mRNA poly(A) tails to regulate eukaryotic mRNA stability and translation. RNA-binding proteins contribute to specificity by interacting with both Ccr4-Not and target mRNAs, but this is not fully understood.
Michael W Webster +2 more
doaj +1 more source
Hemocompatibility poly (lactic acid) nanostructures: A bird’s eye view [PDF]
Nanomedicine Journal, 2020 The usage of clinical devices in the cardiovascular treatment, hemodialyze system and other biomedical applications has improved recently. Direct contacts of biomaterials like poly(lactic acid) biopolymer with blood result in the activating of platelets,
Farnaz-sadat Fattahi, Tahereh Zamani
doaj +1 more source
RNA: A publication of the RNA Society, 2019 Extensive research in the past decade has brought mRNA closer to the clinical realization of its therapeutic potential. One common structural feature for all cellular messenger RNAs is a poly(A) tail, which can either be brought in cotranscriptionally ...
Željka Trepotec +4 more
semanticscholar +1 more source
A Raman spectroscopic study of the interaction between nucleotides and the DNA binding protein gp32 of bacteriophage T4 [PDF]
, 1987 Raman spectra of the bacteriophage T4 denaturing protein gp32, its complex with the polynucleotides poly(rA), poly(dA), poly(dT), poly(rU), and poly(rC), and with the oligonucleotides (dA)8 and (dA)2, were recorded and interpreted.
Greve, J., Mul, F.F.M. de, Otto, C.
core +2 more sources
Preparation and Properties of an Analogue of Poly(A) and Poly(G): Poly(isoguanylic acid) [PDF]
European Journal of Biochemistry, 1976 Isoguanosine-5'-pyrosphosphate, in the presence of an oligonucleotide primer, was polymerized by Escherichia coli polynucleotide phosphorylase under conditions analogous to those required for polymerization of 5'-GMP. The resulting poly(isoguanylic acid), poly(isoG), was a multistranded helix with a stability considerably higher than that of poly(G ...
Zygmunt Kazimierczuk +3 more
openaire +3 more sources
Short Poly(A) Tails are a Conserved Feature of Highly Expressed Genes
Nature Structural & Molecular Biology, 2017 Poly(A) tails are important elements in mRNA translation and stability, although recent genome-wide studies have concluded that poly(A) tail length is generally not associated with translational efficiency in nonembryonic cells.
S. Lima +7 more
semanticscholar +1 more source
K-theory of virtually poly-surface groups [PDF]
, 2002 In this paper we generalize the notion of strongly poly-free group to a larger class of groups, we call them strongly poly-surface groups and prove that the Fibered Isomorphism Conjecture of Farrell and Jones corresponding to the stable topological ...
Roushon, S. K.
core +5 more sources
Sequence specific binding of beta carboline alkaloid harmalol with deoxyribonucleotides: binding heterogeneity, conformational, thermodynamic and cytotoxic aspects. [PDF]
PLoS ONE, 2014 Base dependent binding of the cytotoxic alkaloid harmalol to four synthetic polynucleotides, poly(dA).poly(dT), poly(dA-dT).poly(dA-dT), poly(dG).poly(dC) and poly(dG-dC).poly(dG-dC) was examined by various photophysical and calorimetric studies, and ...
Sarita Sarkar +2 more
doaj +1 more source
The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases
Nature Structural & Molecular Biology, 2019 The 3′ poly(A) tail of messenger RNA is fundamental to regulating eukaryotic gene expression. Shortening of the poly(A) tail, termed deadenylation, reduces transcript stability and inhibits translation.
T. Tang +3 more
semanticscholar +1 more source