Results 81 to 90 of about 25,360,752 (379)

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Temperature patterns in a poly-tubeventilated greenhouse

California Agriculture, 1966
New systems for greenhouse management have been introduced in recent years that necessitate changes in some of the traditional methods of growing greenhouse crops. Evaporative cooling.
P Parvin, R Sciaroni, R Curley
doaj  

Poly(a) selection introduces bias and undue noise in direct RNA-sequencing

BMC Genomics, 2022
Background Genome-wide RNA-sequencing technologies are increasingly critical to a wide variety of diagnostic and research applications. RNA-seq users often first enrich for mRNA, with the most popular enrichment method being poly(A) selection.
Marcus J. Viscardi, Joshua A. Arribere
doaj   +1 more source

Poly(iminomethylenes). 10. Esterolytic catalysis by poly(carbylhistidine) and poly(carbylhistamine) [PDF]

Recueil des Travaux Chimiques des Pays-Bas, 1979
AbstractThe catalytic activities in the hydrolysis of 4‐nitro‐ and 2,4‐dinitrophenyl acetate were determined for a polymer of 3‐(4‐imidazolyl)‐2‐isocyanopropanoic acid (1a) and of 2‐(4‐imidazolyl)‐1‐isocyanoethane (1b). A detailed kinetic analysis has been performed.
Eijk, J.M. van der, Gusdorf, C.F., Nolte, R.J.M., Drenth, W.   +3 more
openaire   +4 more sources

Interaction of magnesium ions with poly A and poly U [PDF]

Biopolymers, 1971
AbstractThe binding of Mg++ to poly A and poly U has been measured quantitatively by using the metallochromic indicator calmagite. The method is described in detail. It is shown that there is electrostatic interaction between the binding sites, viz., the phosphate groups, and the intrinsic association constant, for the specific binding can be ...
Willemsen, A.M., Os, G.A.J. Van
openaire   +4 more sources

APASdb: a database describing alternative poly(A) sites and selection of heterogeneous cleavage sites downstream of poly(A) signals

Nucleic Acids Res., 2014
Increasing amounts of genes have been shown to utilize alternative polyadenylation (APA) 3′-processing sites depending on the cell and tissue type and/or physiological and pathological conditions at the time of processing, and the construction of genome ...
Leiming You, Jiexin Wu, Yuchao Feng, Yonggui Fu, Yanan Guo, Liyuan Long, Hui Zhang, Yi Luan, P. Tian, Liangfu Chen, Guangrui Huang, Shengfeng Huang, Yuxin Li, Jie Li, Chengyong Chen, Yaqing Zhang, Shangwu Chen, A. Xu   +17 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Synthesis of Optically Active Poly(diphenylacetylene)s Using Polymer Reactions and an Evaluation of Their Chiral Recognition Abilities as Chiral Stationary Phases for HPLC

Molecules, 2016
A series of optically active poly(diphenylacetylene) derivatives bearing a chiral substituent (poly-2S) or chiral and achiral substituents (poly-(2Sx-co-31−x)) on all of their pendant phenyl rings were synthesized by the reaction of poly(bis(4 ...
Katsuhiro Maeda, Miyuki Maruta, Yuki Sakai, Tomoyuki Ikai, Shigeyoshi Kanoh   +4 more
doaj   +1 more source

Phase Behavior of Polyelectrolyte Block Copolymers in Mixed Solvents

, 2008
We have studied the phase behavior of the poly(n-butyl acrylate)-b-poly(acrylic acid) block copolymer in a mixture of two miscible solvents, water and tetrahydrofuran (THF).
Ballauff M., Bendejacq D., Bendejacq D., Bendejacq D., Bendejacq D., Bendejacq D., Berret J.-F., Berret J.-F., Berret J.-F., Berret J.-F., Brandrup J., Cao H., Charmot D., Choucair A., Cui H., Destarac M., Dhont J. K. G., Eghbali E., Förster S., Gaillard N., Garnier S., Gast A. P., Groenewegen W., Halperin A., Hariharan R., Hariharan R., Hervé P., Jacquin M., Jacquin M., Johnson B. K., Lee A. S., Li Y., Lindner P., Luo L., Luo L., Muller F., Muller F., Nagarajan R., Nikova A. T., Pedersen J. S., Pham Q. T., Pham Q. T., Pochan D. J., Riess G., Roger M., Shen H., Su W., Séréro Y., van der Maarel J. R. C., Willner L., Willner L., Yang C., Zhang L.   +52 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source