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In vivo testing of crosslinked polyethers. II. Weight loss, IR analysis, and swelling behavior after implantation [PDF]
As reported in Part I (In vivo testing of crosslinked polyethers. I. Tissue reactions and biodegradation, J. Biomed. Mater. Res., this issue, pp.
Bantjes, A +4 more
core +31 more sources
Various composites with nanosilicas, as well as with other nanooxides, and polymers are of importance from a practical point of view. Detailed textural and morphological characterization, applied here to nanosilicas treated alone and in composites with ...
V. M. Gun'ko
doaj +1 more source
Biofouling on surfaces, caused by the assimilation of proteins, peptides, lipids and microorganisms, leads to contamination, deterioration and failure of biomedical devices and causes implants rejection.
Jesna Ashraf +6 more
doaj +1 more source
Promising Therapeutic Targets for Treatment of Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a systemic poly-articular chronic autoimmune joint disease that mainly damages the hands and feet, which affects 0.5% to 1.0% of the population worldwide.
Jie Huang +6 more
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Gene dosage effects of poly(A) track-engineered hypomorphs
Manipulation of gene activity through creation of hypomorphic mutants has been a long-standing tool in examining gene function. Our previous studies have indicated that hypomorphic mutants could be created by inserting cis-regulatory sequences composed ...
Geralle Powell +2 more
doaj +1 more source
HIV protease cleaves poly(A)-binding protein [PDF]
The PABP [poly(A)-binding protein] is able to interact with the 3′ poly(A) tail of eukaryotic mRNA, promoting its translation. Cleavage of PABP by viral proteases encoded by several picornaviruses and caliciviruses plays a role in the abrogation of cellular protein synthesis.
Álvarez, Enrique +3 more
openaire +3 more sources
Evidence that Poly(A) Binding Protein C1 Binds Nuclear Pre-mRNA Poly(A) Tails [PDF]
In mammalian cells, poly(A) binding protein C1 (PABP C1) has well-known roles in mRNA translation and decay in the cytoplasm. However, PABPC1 also shuttles in and out of the nucleus, and its nuclear function is unknown. Here, we show that PABPC1, like the major nuclear poly(A) binding protein PABPN1, associates with nuclear pre-mRNAs that are ...
Nao, Hosoda +2 more
openaire +2 more sources
One‐Step Synthesis of Hydrogen‐Bonded Microcapsules for pH‐Triggered Protein Release
One‐step microfluidic approach in which interfacial complexation of hydrogen bonding polymers is utilized to prepare pH‐responsive microcapsules is presented.
Leekang Jeon +4 more
doaj +1 more source
TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand
TLR3 plays a crucial role in anti-viral immune response by recognizing RNAs produced during virus infection. Here, the authors determine a high resolution structure of the activated cluster of TLR3.
Chan Seok Lim +6 more
doaj +1 more source
Drying processes such as spray drying, as commonly used in the pharmaceutical industry to convert protein-based drugs into their particulate form, can lead to an irreversible loss of protein activity caused by protein secondary structure changes.
Julian F. A. Perlitz +3 more
doaj +1 more source

