Study of the functional product’s protein compounds digestion features
Теория и практика переработки мяса, 2020 The aim of the study was to investigate the transformation of meat product’s proteins from pig hearts and aortas during enzymatic hydrolysis in an in vitro model of the gastrointestinal tract.
E. R. Vasilevskaya +3 more
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Rotavirus NSP3 Is a Translational Surrogate of the Poly(A) Binding Protein-Poly(A) Complex [PDF]
Journal of Virology, 2015 ABSTRACT Through its interaction with the 5′ translation initiation factor eIF4G, poly(A) binding protein (PABP) facilitates the translation of 5′-capped and 3′-poly(A)-tailed mRNAs. Rotavirus mRNAs are capped but not polyadenylated, instead terminating in a 3′ GACC motif that is recognized by the viral protein NSP3, which competes ...
Gratia, Matthieu +7 more
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Polymeric membranes with selective permeability : shielding of an antioxidant enzyme [PDF]
, 2008 In this work we designed an antioxidant nanoreactor based on the encapsulation of CuZnSOD in amphiphilic copolymer nanovesicles. The nanovesicles are formed by self-assembly of amphiphilic copolymer poly-(2-methyloxazoline)-poly- (dimethylsiloxane ...
Axthelm, Fabian
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Poly(A) Nuclease Interacts with the C-terminal Domain of Polyadenylate-binding Protein Domain from Poly(A)-binding Protein [PDF]
Journal of Biological Chemistry, 2007 The poly(A)-binding protein (PABP) is an essential protein found in all eukaryotes and is involved in an extensive range of cellular functions, including translation, mRNA metabolism, and mRNA export. Its C-terminal region contains a peptide-interacting PABC domain that recruits proteins containing a highly specific PAM-2 sequence motif to the ...
Nadeem, Siddiqui +5 more
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Biomimetic superstructures from amphiphilic ABA-triblock copolymers [PDF]
, 2005 The spontaneous formation of nanostructured materials by molecular self-assembly of block copolymers is an active area of research, driven both by its inherent beauty and by a wealth of potential technological applications. The so-called “supramolecular”
Grumelard, Julie
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Immunodetection of Poly(A) Binding Protein II in the Cell Nucleus [PDF]
Experimental Cell Research, 1994 During the polyadenylation of pre-mRNA in vitro, poly(A) binding protein II (PAB II) binds to the growing poly(A) tail, stimulating its extension. The subcellular localization of PAB II was investigated with an antibody affinity-purified from rabbit serum raised against the purified protein.
Krause, Sabine +3 more
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Prenatal activation of toll-like receptors-3 by administration of the viral mimetic poly(I:C) changes synaptic proteins, N-methyl-D-aspartate receptors and neurogenesis markers in offspring [PDF]
, 2012 Background - There is mounting evidence for a neurodevelopmental basis for disorders such as autism and schizophrenia, in which prenatal or early postnatal events may influence brain development and predispose the young to develop these and related ...
Stone, T.W. +5 more
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Inhibition of tristetraprolin deadenylation by poly(A) binding protein
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2008 Tristetraprolin (TTP) is the prototype for a family of RNA binding proteins that bind the tumor necrosis factor (TNF) messenger RNA AU-rich element (ARE), causing deadenylation of the TNF poly(A) tail, RNA decay, and silencing of TNF protein production. Using mass spectrometry sequencing we identified poly(A) binding proteins-1 and -4 (PABP1 and PABP4)
Robert M, Rowlett +9 more
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Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome
Cell Reports, 2023 Summary: Expansion of the hexanucleotide repeat GGGGCC in the C9orf72 gene is the most common genetic factor in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Xiaoqiu Shu +11 more
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Lateral diffusion processes in biomimetic polymer membranes [PDF]
, 2015 Molecular self-assembly offers an important bottom-up approach to generate new materials with great potential for applications in nano-, life- and medical- sciences and engineering.
Itel, Fabian
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