Platelet deposition studies on copolyether urethanes modified with poly(ethylene oxide) [PDF]
, 1990 Pellethane ® 2363 80A films and tubings were chemically modified and the effect of these modifications on platelet deposition was studied. Grafting of high molecular weight poly(ethylene oxide) and graft polymerization of methoxy poly(ethylene glycol ...
Bantjes, A. +3 more
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General RNA‐binding proteins have a function in poly(A)‐binding protein‐dependent translation [PDF]
The EMBO Journal, 2008 The interaction between the poly(A)-binding protein (PABP) and eukaryotic translational initiation factor 4G (eIF4G), which brings about circularization of the mRNA, stimulates translation. General RNA-binding proteins affect translation, but their role in mRNA circularization has not been studied before.
Svitkin, Yuri V. +10 more
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Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin. [PDF]
, 2012 Sirtuins (SIRTs) and poly(ADP-ribose) polymerases (PARPs), NAD(+)-dependent enzymes, link cellular energy status with responses to environmental stresses.
Benavente, Claudia A +2 more
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Identification of proteins associating with poly(A)‐binding‐protein mRNA [PDF]
European Journal of Biochemistry, 1992 Synthesis of poly(A)‐binding protein is regulated at the translational level. We have investigated the binding of proteins to this mRNA on the premise that the protein(s) of the mRNP complex may be involved in regulating the expression of the mRNA. We found the first 243 nucleotides of the 5′ untranslated region to contain sequences essential for RNP ...
L C, Berger, J, Bag, B H, Sells
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ER5, a tomato cDNA encoding an ethylene-responsive LEA-like protein: characterization and expression in response to drought, ABA and wounding [PDF]
, 1997 We report the isolation by differential display of a novel tomato ethylene-responsive cDNA, designated ER5. RT-PCR analysis of ER5 expression revealed an early (15 min) and transient induction by ethylene in tomato fruit, leaves and roots.
Bouzayen, Mondher +6 more
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PUB1: a Major Yeast Poly(A)+ RNA-Binding Protein [PDF]
Molecular and Cellular Biology, 1993 The expression of RNA polymerase II transcripts can be regulated at the posttranscriptional level by RNA-binding proteins. Although extensively characterized in metazoans, relatively few RNA-binding proteins have been characterized in the yeast Saccharomyces cerevisiae.
M J, Matunis, E L, Matunis, G, Dreyfuss
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Cas Adaptor Proteins Coordinate Sensory Axon Fasciculation. [PDF]
, 2018 Development of complex neural circuits like the peripheral somatosensory system requires intricate mechanisms to ensure axons make proper connections. While much is known about ligand-receptor pairs required for dorsal root ganglion (DRG) axon guidance ...
Estep, Jason A +5 more
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Identification of a novel Xenopus laevis poly (A) binding protein [PDF]
Biology of the Cell, 2004 Summry— Poly (A) binding proteins are intimately implicated in controlling a number of events in mRNA metabolism from nuclear polyadenylation to cytoplasmic translation and stability. The known poly(A) binding proteins can be divided into three distinct structural groups (prototypes PABP1, PABPN1/PABP2 and Nab2p) and two functional families, showing ...
Cosson, Bertrand +4 more
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Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome
Cell Reports, 2023 Summary: Expansion of the hexanucleotide repeat GGGGCC in the C9orf72 gene is the most common genetic factor in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Xiaoqiu Shu +11 more
doaj +1 more source
Rrp6p Controls mRNA Poly(A) Tail Length and Its Decoration with Poly(A) Binding Proteins [PDF]
Molecular Cell, 2012 Poly(A) (pA) tail binding proteins (PABPs) control mRNA polyadenylation, stability, and translation. In a purified system, S. cerevisiae PABPs, Pab1p and Nab2p, are individually sufficient to provide normal pA tail length. However, it is unknown how this occurs in more complex environments.
Schmid M +8 more
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