Results 111 to 120 of about 285,813 (286)
Mechanisms governing poly(A)-tail-length specificity of the human PAN2-PAN3 deadenylase complex
Cell ReportsSummary: The lifespan of most eukaryotic mRNAs is modulated by the gradual shortening of the poly(A) tail and removal of the associated poly(A)-binding protein.
Jana C. Albrecht +6 more
doaj +1 more source
CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State
Stem Cell Reports, 2016 Poly(A) tail length and mRNA deadenylation play important roles in gene regulation. However, how they regulate embryonic development and pluripotent cell fate is not fully understood.
Xiaofeng Zheng +13 more
doaj +1 more source
Capturing the ‘ome’ : the expanding molecular toolbox for RNA and DNA library construction [PDF]
, 2018 All sequencing experiments and most functional genomics screens rely on the generation of libraries to comprehensively capture pools of targeted sequences.
Boone, Morgane +2 more
core +2 more sources
Polymer Network Modified Perovskite for High‐Performance Pure Blue Light‐Emitting Diodes
Advanced Functional Materials, EarlyView.A polymer network of poly(4‐vinylphenol) (PVPh) is introduced to improve pure blue perovskite light‐emitting diodes. PVPh effectively passivates defects, enhances film morphology, reduces lattice strain, and suppresses ion migration. These effects lead to record device performance, achieving 9.82% external quantum efficiency and stable blue emission at
Zhongkai Yu +11 more
wiley +1 more source
Nab2, a Three-Cornered Hat to Bind a Poly(A) Tail [PDF]
Structure, 2012 In this issue of Structure, Brockman and co-workers reveal the structure and interactions of Nab2 with polyadenosine RNA, which marks the completion of 3' end processing and initiates the assembly of mRNA and carrier proteins for export through the nuclear pore complex.
openaire +2 more sources
Advanced Functional Materials, EarlyView.Conjugated polymer–nanocrystal composites are investigated to develop fast, high‐yield green scintillators. The polymer F8BT enables efficient, ultrafast emission, while blends with non‐emitting HfO2 nanocrystals and luminescent CdZnS/ZnS quantum dots reveal distinct sensitization mechanisms.
Chenger Wang +13 more
wiley +1 more source
Lsm14b controls zebrafish oocyte growth by regulating polyadenylation of the mRNA poly(A) tail
Frontiers in Marine ScienceLsm14b (LSM family member 14b) is a messenger ribonucleoprotein (mRNP) and a widely present component in eukaryotes. Lsm14b participates in oocyte development by regulating mRNA translation, however, the specific translational regulatory mechanisms ...
Xingxing Wu +6 more
doaj +1 more source
Nature Communications, 2019 The poly(A) tails on mRNA are vital for their function but it is difficult to map full-length sequences of mRNA isoforms with the entire poly(A) tails.
Yusheng Liu +3 more
doaj +1 more source
Cyclic Olefin Copolymers as Versatile Materials for Advanced Engineering Applications
Advanced Functional Materials, EarlyView.Cyclic olefin copolymers (COCs) are presented as highly versatile materials combining tunable synthesis, excellent optical properties, and mechanical robustness. Their potential spans microfluidics, bioengineering, and advanced electronics, while emerging self‐healing and sustainable solutions highlight future opportunities.
Giulia Fredi +3 more
wiley +1 more source
Advanced Functional Materials, EarlyView.The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett +19 more
wiley +1 more source