Results 121 to 130 of about 114,953,758 (241)
Helicopter tail rotor thrust and main rotor wake coupling in crosswind flight [PDF]
, 2010 The tail rotor of a helicopter with a single main rotor configuration can experience a significant reduction in thrust when the aircraft operates in crosswind flight. Brown’s vorticity transport model has been used to simulate a main rotor and tail rotor
Fletcher, Timothy M., Brown, Richard
core +1 more source
Advanced Materials, EarlyView.The mechanical performance of nanocellular polyetherimide cannot be explained by nanoporosity alone. It is shown that CO2 saturation and desorption leave a distinct mechanical signature in the glassy matrix before foaming. This matrix contribution provides a new route to understand and optimize the brittle to ductile transition in nanocellular polymers.
Félix Lizalde‐Arroyo +7 more
wiley +1 more source
Encapsulation of mRNA into Artificial Viral Capsids via Hybridization of a β-Annulus-dT20 Conjugate and the Poly(A) Tail of mRNA [PDF]
Messenger RNA (mRNA) drugs have attracted considerable attention as promising tools with many therapeutic applications. The efficient delivery of mRNA drugs using non-viral materials is currently being explored.
Matsuura, Kazunori +23 more
core +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Advanced Materials, EarlyView.A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian +7 more
wiley +1 more source
Advanced Materials, EarlyView.This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris +11 more
wiley +1 more source
Function and regulation of poly(A)-tail length
, 2014 Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, June 2014.Cataloged from PDF version of thesis. "May 2014." Vita.Includes bibliographical references.Poly(A) tails are found at the 3' ends of nearly all eukaryotic messenger ...
Subtelny, Alexander O. (Alexander Orest)
core
Single‐Particle FRET Probes Heterogeneity in the Ligand Shell of Colloidal Perovskite Quantum Dots
Advanced Materials, EarlyView.Single‐particle, single‐molecule Förster resonance energy transfer turns dye‐tagged ligands into nanorulers for the otherwise elusive organic shell of CsPbBr3 quantum dots. Distance variations within individual particles reveal pronounced local heterogeneity, while changes in the surrounding ligand chemistry shift the average dye–surface separation ...
Leon G. Feld +6 more
wiley +1 more source
Ccr4 and Pop2 control poly(A) tail length in Saccharomyces cerevisiae
, 2017 Messenger RNA degradation is an important aspect of post-transcriptional gene regulation and shortening the poly(A) tail is suggested to be the rate-limiting step in mRNA degradation.
Jeff Coller +4 more
core +1 more source
Advanced Materials, EarlyView.A novel selective laser sintering and graphitization (SLSG) 3D printing technology enables unibody fabrication of compacted insulating structures and conductive circuits in fluidic‐integrated wearable electronics through adaptive photonic modulation.
Li Zhang, Wing Cheung Mak
wiley +1 more source