Results 131 to 140 of about 283,934 (290)

Alternative Splicing and Polyadenylation Contribute to the Generation of hERG1 C-terminal Isoforms

open access: yes, 2010
The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit of the rapidly activating delayed rectifier potassium channel. Several hERG1 isoforms with different N- and C-terminal ends have been identified.
Gong, Qiuming   +4 more
core  

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

open access: yesAdvanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández   +7 more
wiley   +1 more source

Breathable Graphene Oxide‐Polymer Composite Membranes With Two‐Step Barrier Mechanism Against Nerve Agents

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Breathable membranes that reject chemical warfare agents (CWAs) are required for next‐generation protective apparel. A dual‐function graphene oxide (GO)‐polyamine architecture is introduced that addresses the long‐standing tradeoff between vapor transmission and CWA selectivity.
Hyungjun Kim   +6 more
wiley   +1 more source

Sensorized Engineered Tissues with Built‐in Thermoregulation and Nutrient Supply

open access: yesAdvanced Functional Materials, EarlyView.
This work introduces a granular hydrogel‐based tissue engineering platform that includes a closed‐loop temperature control to maintain 37°C and sustainably releases nutrients, thereby enabling cells to retain a high viability even if stored at room temperature for up to 24 h.
Antonia Georgopoulou   +5 more
wiley   +1 more source

Controlled method of reducing electrophoretic mobility of macromolecules, particles, or cells [PDF]

open access: yes, 1992
A method of reducing electrophoretic mobility of macromolecules, particles, cells, and other substances is provided which comprises interacting in a conventional electrophoretic separating procedure, the substances with a polymer-linked affinity compound
Vanalstine, James M.
core   +1 more source

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

open access: yesAdvanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal   +9 more
wiley   +1 more source

Dynamic Bonds Enable Repair and Reprocessing of Glycol‐Modified PET

open access: yesAdvanced Functional Materials, EarlyView.
Dynamic hindered urea bonds enable rapid healing in glycol‐modified PET‐based polyurethanes. Tuning the hindered‐amine content allows these polymers to balance mechanical integrity with fast repair, achieving complete scratch disappearance in 30 s at 130°C.
Chaninya Mak‐iad   +3 more
wiley   +1 more source

Artifact‐Minimizing Ultrathin Transparent Electrodes Fabricated via iCVD for In Vivo Optogenetic Stimulation and Neural Signal Monitoring of Primary Visual Cortex

open access: yesAdvanced Functional Materials, EarlyView.
We present ultrathin flexible transparent electrodes through iCVD‐enabled molecular control of 10 nm gold films on poly(dimethylaminomethylstyrene). In vivo validation demonstrated photoelectric artifact reduction vs. opaque electrodes and preservation of natural neural dynamics.
Tae Jin Mun   +11 more
wiley   +1 more source

Mechanochromism of Glassy Polymers Enabled by a Loop‐Forming Supramolecular Mechanophore

open access: yesAdvanced Functional Materials, EarlyView.
The supramolecular mechanophore LOOP is covalently introduced into glassy polymers, capable of reporting force‐induced pre‐failure damage and local fracture events in polymer glasses. Under different mechanical deformation modes, including grinding, tensile stretching, and scratching, LOOP probes irreversible events in polymer glasses through a ...
Linlin Deng   +6 more
wiley   +1 more source

Multiple C-Terminal Tails within a Single \u3cem\u3eE. coli\u3c/em\u3e SSB Homotetramer Coordinate DNA Replication and Repair [PDF]

open access: yes, 2013
Escherichia coli single-stranded DNA binding protein (SSB) plays essential roles in DNA replication, recombination and repair. SSB functions as a homotetramer with each subunit possessing a DNA binding domain (OB-fold) and an intrinsically disordered C ...
Antony, Edwin   +7 more
core   +1 more source

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