Results 171 to 180 of about 657,615 (203)
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Poly(adenosine diphosphate ribose)
1973Publisher Summary This chapter discusses that incorporation of radioactivity of (adenine- 14 C) ATP into the acid insoluble material in a nuclear preparation from hen liver is enhanced at least 1000-fold by the presence of NMN. It is confirmed that this stimulation: using a nuclear preparation from rat liver.
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Nonenzymic adenosine 5'-diphosphate ribosylation of poly(adenosine diphosphate ribose).
Biochemistry, 1986Poly(adenosine 5'-diphosphate ribose) [poly(ADP-ribose]) is spontaneously ADP-ribosylated when it is incubated with nicotinamide adenine dinucleotide, especially in 0.5 M NaCl and at an alkaline pH. The ADP-ribose residues are monomeric and are attached to the middle of polymer chains.
M, Ikejima, D M, Gill
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Purification and characterization of human lymphoid poly(adenosine diphosphate ribose) polymerase
Biochemistry, 1982Poly(ADP-ribose) polymerase has been purified 12 000-fold from human tonsils with an 83% recovery of enzymatic activity relative to that of the initial homogenate. The specific activity of the purified enzyme is 862 units/mg of protein. The isolated protein has a molecular weight of approximately 116 000 as determined by sodium dodecyl sulfate ...
S G, Carter, N A, Berger
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IMMUNOHISTOCHEMICAL DEMONSTRATION OF POLY(ADENOSINE DIPHOSPHATE‐RIBOSE) SYNTHESIS IN HUMAN SKIN
The Journal of Dermatology, 1982ABSTRACTThe distribution of poly(adenosine diphosphate‐ribose) [poly(ADP‐ribose)] synthesis in human skin was investigated by an indirect immunofluorescence technique using a specific antibody against poly(ADP‐ribose). In normal skin, the specific immunofluorescence of poly(ADP‐ribose) was observed in nuclei of not only epidermal cells but also cells ...
K, Ikai, K, Danno, S, Imamura, K, Ueda
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A new method for the assay of poly(adenosine diphosphate ribose) glycohydrolase activity
Analytical Biochemistry, 1975Poly(adenosine diphosphate ribulose) [poly(ADP-Rib)] glycohydrolase activity was determined by measuring the amount of ADP-Rib hydrolyzed from polymers of ADP-Rib as substrate. In principle, the method consists of incubating oligomers or polymers of [14C]ADP-Rib with testis glycohydrolase.
L O, Burzio, P T, Riquelme, S S, Koide
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Monoclonal antibodies to poly(adenosine diphosphate ribose) recognize different structures
Biochemistry, 1984Two hybridomas producing monoclonal antibodies to poly(adenosine diphosphate ribose) [poly(ADP-Rib)] were established. One antibody, 10H (IgG3, kappa), bound to most of the poly(ADP-Rib) preparation, which consisted of molecules of various sizes of more than 20 ADP-Rib residues.
H, Kawamitsu +5 more
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Synthesis of poly(adenosine diphosphate ribose) in synchronized Chinese hamster cells
Experimental Cell Research, 1978Abstract Chinese hamster ovary cells were synchronized by mitotic selection and used to study the relation of poly(adenosine diphosphate ribose) synthesis to DNA synthesis and the different phases of the cell cycle. DNA synthesis was measured in cells rendered permeable to exogenously supplied nucleotides.
N A, Berger +5 more
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Inhibition of poly(adenosine diphosphate-ribose) polymerase using quinazolinone nucleus
Applied Microbiology and Biotechnology, 2016Poly(adenosine diphosphate-ribose) polymerase (PARP) is a group of enzymes with several subtypes and it manages various ailment such as cancer, inflammatory disorders, diabetes mellitus, neuronal injury, HIV infection, Parkinsonism, aging, and ischemia-reperfusion injury.
K, Hemalatha, G, Madhumitha
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Studies on poly (adenosine diphosphate-ribose)
Archives of Biochemistry and Biophysics, 1971Michiyuki Yamada +2 more
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