Results 171 to 180 of about 3,094 (198)
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Chromosomal protein poly(ADP-ribosyl)ation in pancreatic nucleosomes
Canadian Journal of Biochemistry, 1982When pancreatic chromatin fragments were prepared and resolved in the presence of 80 mM NaCl, endogenous poly(ADP-ribose) polymerase activity was found to be maximal in nucleosome periodicities of four to five units and did not respond to any further increases in nucleosomal architecture.
R J, Aubin +4 more
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[45] Overview of poly(ADP-ribosyl)ation
1984Publisher Summary This chapter provides an overview of poly(ADP-ribosyl)ation. The formation of poly(ADP-ribose) by chromatin enzymes is actually initiated by ADP-ribosylation on chromatin proteins. The ADP-ribosylation reaction is catalyzed by enzymes which transfer the ADP-ribose residue of NAD + to various acceptor proteins.
Mark E. Smulson, Takashi Sugimura
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Modulation of chromatin structure by poly(ADP-ribosyl)ation.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 1988Poly(ADP-ribose) polymerase is a nuclear enzyme that is highly conserved in eucaryotes. Its activity is totally dependent on the presence of DNA containing single or double stranded breaks. We have shown that this activation results in a decondensation of chromatin superstructure in vitro, which is caused mainly by hyper(ADP-ribosy)ation of histone H1.
Murcia, G, Huletsky, A, Poirier, G G
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Poly(ADP-ribosyl)ation in asthma and other lung diseases
Pharmacological Research, 2005Inhibition of poly(ADP-ribosyl)ation in oxidative stress-related pathologies has recently emerged as a very effective anti-inflammatory intervention in animal models of arthritis, colitis, diabetes and shock. Recent data from three laboratories also support the role of poly(ADP-ribose) polymerase-1 (PARP-1) activation in asthma.
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Genomic Maintenance: The p53 Poly(ADP-ribosyl)ation Connection
Science's STKE, 2007The integrity of the genome in higher eukaryotes, as well as the modulation of its complex structure and functions, is exquisitely regulated. This genomic regulation occurs as a function of time in a very sophisticated and elaborate biological process called cell cycle progression, resulting in cell division, and is also controlled by a highly ...
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The role of poly(ADP-ribosyl)ation
1997S L, Oei, J, Griesenbeck, M, Schweiger
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Effect of zinc on cellular poly(ADP-ribosyl)ation capacity
Experimental Gerontology, 2008George V Dedoussis +2 more
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