Results 151 to 160 of about 6,825 (206)

Increased DNA Damage in Progression Of COPD: A Response By Poly(ADP-Ribose) Polymerase-1 [PDF]

, 2017
Altraja, Alan, Oit,-Wiscombe, Ingrid, Soomets, Ursel, Virág, László   +3 more
core   +1 more source

Poly(ADP-ribosyl)ation of FOXP3 protein mediated by PARP-1 regulates the function of regulatory T cells. [PDF]

J Biol Chem, 2016
Luo X, Nie J, Wang S, Chen Z, Chen W, Li D, Hu H, Li B.   +7 more
europepmc   +1 more source

Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo. [PDF]

Nucleic Acids Res, 2017
Schuhwerk H, Bruhn C, Siniuk K, Min W, Erener S, Grigaravicius P, Krüger A, Ferrari E, Zubel T, Lazaro D, Monajembashi S, Kiesow K, Kroll T, Bürkle A, Mangerich A, Hottiger M, Wang ZQ.   +16 more
europepmc   +1 more source

The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1. [PDF]

Nucleic Acids Res, 2018
Fischbach A, Krüger A, Hampp S, Assmann G, Rank L, Hufnagel M, Stöckl MT, Fischer JMF, Veith S, Rossatti P, Ganz M, Ferrando-May E, Hartwig A, Hauser K, Wiesmüller L, Bürkle A, Mangerich A.   +16 more
europepmc   +1 more source

PARP1-mediated PPARα poly(ADP-ribosyl)ation suppresses fatty acid oxidation in non-alcoholic fatty liver disease. [PDF]

J Hepatol, 2017
Huang K, Du M, Tan X, Yang L, Li X, Jiang Y, Wang C, Zhang F, Zhu F, Cheng M, Yang Q, Yu L, Wang L, Huang D, Huang K.   +14 more
europepmc   +1 more source

Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death [PDF]

, 2019
al., et, Ellenberger, Tom, Houl, Jerry H., Kim, In-Kwon, Stegeman, Roderick A.   +4 more
core   +1 more source

Poly(ADP-ribosyl)ation of FOXP3 Protein Mediated by PARP-1 Protein Regulates the Function of Regulatory T Cells. [PDF]

J Biol Chem, 2015
Luo X, Nie J, Wang S, Chen Z, Chen W, Li D, Hu H, Li B.   +7 more
europepmc   +1 more source

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal. [PDF]

Nature, 2015
DaRosa PA, Wang Z, Jiang X, Pruneda JN, Cong F, Klevit RE, Xu W.   +6 more
europepmc   +1 more source

Tankyrase1-mediated poly(ADP-ribosyl)ation of TRF1 maintains cell survival after telomeric DNA damage. [PDF]

Nucleic Acids Res, 2017
Yang L, Sun L, Teng Y, Chen H, Gao Y, Levine AS, Nakajima S, Lan L.   +7 more
europepmc   +1 more source

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Poly(ADP-ribosyl)ation and stroke

Pharmacological Research, 2005
Over the past decade, poly(ADP-ribosyl)ation has emerged as a crucial event in the pathogenesis of ischemic stroke. A large body of evidence unambiguously demonstrates that activity of poly(ADP-ribose) polymerase-1 (PARP-1) significantly increases during brain ischemia, and that inhibition of this enzymatic activity affords substantial neuroprotection ...
Alberto Chiarugi
exaly   +3 more sources