Results 1 to 10 of about 580,970 (120)
Helix-with-Loops Structure of Polynucleotide. I. Poly(C+IC) and Poly(C+GU) [PDF]
Bulletin of the Chemical Society of Japan, 1967 Abstract A copolymer of 57% riboinosinic acid plus 43% ribocytidylic acid has been prepared. The ultraviolet absorbances of aqueous solutions of mixtures of this copolymer and polyribocytidylic acid of various mole ratios were measured. The results indicate that, in these aqueous solutions, a “helix-with-loops” structure is formed; this ...
T, Ichikawa +3 more
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Integrity of Cell-bound Poly(I).Poly(C)
Journal of General Virology, 1974 Summary The acid-insoluble radioactivity associated with the cells following incubation of the cells with [3H]-labelled poly(I).poly(C) [poly(I).poly(C) * for 1 h has been analysed by sucrose gradient velocity ultracentrifuging. Intact (poly(I).poly(C) * was recovered from primary rabbit kidney (PRK) cells, partially degraded poly(I).
E, De Clercq, W E, Stewart
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Interaction of poly(I)·poly(C) with trans‐dichloro‐diammine‐platinum (II) [PDF]
Biopolymers, 1984 AbstractThe covalent binding of trans‐Pt (NH3)2Cl2 to the double‐stranded poly(I)·poly(C) follows three types of reactions, depending on rb and the concentration of polynucleotide in the reaction mixture. At rb ⩽ 0.1, the principal reaction is coordination to poly(I), giving rise to some destabilization of the double strand, as shown by uv and CD ...
D, Hermann +3 more
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Evidence for a three stranded complex between poly I and poly C [PDF]
FEBS Letters, 1968 The conditions for the formation of a triple stranded semi‐protonated complex between polyinosinic (poly (I)) and polycytidylic acid (poly (C)) are described. From potentiometric titrations and mixing curves, the stoichiometry and a phase‐transition diagram is established between the partly protonated triple stranded and the unprotonated and completely
Thiele, Danielle, Guschlbauer, Wilhelm
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Adjuvant effects on poly I poly C in New Zealand mice [PDF]
Arthritis & Rheumatism, 1972 AbstractThe effects of polyinosinic polycytidylic acid (poly l poly C), a known adjuvant, were studied in New Zealand and C57B1/6 mice, using sheep erythrocytes (SRBC) as antigens. The control C57B1/6 mice showed a 3.1 to 6.7 fold increase in plaque forming cells (PFC) to SRBC when poly l poly C was given with the SRBC. The New Zealand mice (NZB/NZW F1
M E, Jacobs +3 more
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Interferon Induction by Poly(I):Poly(C) Enclosed in Phospholipid Particles [PDF]
Infection and Immunity, 1974 Liposomes were prepared with phospholipids (sphingomyelin, lecithin, and phosphatidylethanolamine) in combination with cholesterol and charged lipids (dicetyl phosphate and stearylamine) and contained either poly(I):poly(C) or poly(I). Neutral and positively charged liposomes attached much better to L-929 cells in tissue culture than did ...
S X, Straub, R F, Garry, W E, Magee
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Recognition of polynucleotides by antibodies to poly(1).Poly(C)
Nucleic Acids Research, 1976 The binding of anti poly(I). poly (C) Fab fragments to double or triple stranded polynucletides has been studied by fluorescence. Association constants were deduced from competition experiments. The comparison of the association constants leads to the conclusion that several atoms of the base residues do not interact with the amino acid residues of the
M, Guigues, M, Leng
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Inhibition of Biologic Activity of Poly I: Poly C by Human Plasma
Experimental Biology and Medicine, 1970 SummaryHuman serum and plasma have been shown to abolish the pyrogenicity of poly I:poly C. Chicken serum and, to a lesser extent, fetal calf serum also possess this inhibitory effect, while serums of six other animal species do not alter the pyrogenic properties of this compound.
J J, Nordlund, S M, Wolff, H B, Levy
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The Thermodynamic Characterization of Poly(I)·Poly(C) Duplex–Aminoacridine Dye System [PDF]
Polymer Journal, 1983 Thermodynamic quantities of dyes (proflavine, PF and 9-aminoacridine, 9AA) bound to the poly(I)·poly(C) duplex in the intercalation process have been evaluated from measurement of the heat of mixing. The free energy change for the duplex–PF system is smaller than that for the duplex–9AA system, indicating that the intercalation of PF into the poly(I ...
Kano, Kazuo +3 more
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A New Polynucleotide Complex Poly(s2C) · poly(I) [PDF]
European Journal of Biochemistry, 1972 Poly(s2C) · poly(I) complex formation (where s2C = 2‐thiocytidylate) was shown by spectrophotometric titration, absorption‐difference spectroscopy and hydroxyl‐ion titration. The absorption temperature profile of the complex does not display a transition between 10 and 100°C.
P, Faerber, K H, Scheit, H, Sommer
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