Results 1 to 10 of about 1,913 (163)
Pioneering Role of T.C. Merigan in the Treatment of Various Virus Infections [PDF]
MoleculesThe research of Prof. Dr. Thomas C. Merigan has spanned almost half a century. It started in 1963 with his interest in interferon (i). He then identified pyran copolymer as a synthetic polyanionic inducer of interferon (ii), and thereafter thiophosphate ...
Erik De Clercq
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Polyribonucleotides as Templates for Polydeoxyribonucleotides [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1963 Liebe F Cavalieri, L F Cavalieri
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The Biosynthesis of RNA: Priming by Polyribonucleotides [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1962 S B Weiss, Samuel B. Weiss
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Lack of Fidelity in the Translation of Synthetic Polyribonucleotides^(*) [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1964 I Bernard Weinstein +2 more
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Spin-labeled polyribonucleotides [PDF]
Nucleic Acids Research, 1980 Poly (U), poly (C) and poly (A) were spin labeled with N-(2,2,5,5-tetramethyl-3-carbonylpyrroline-1-oxyl)-imidazole. This spin label interacts selectively with 2' OH ribose groups of polynucleotides and does not modify the nucleic acid bases. The extent of spin labeling is not dependent upon the nature of the base and is entirely determined by rigidity
A I, Petrov, B I, Sukhorukov
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The synthesis of polyribonucleotides by cytoplasmic enzymes [PDF]
Biochemical Journal, 1966 1. The possibility that the cell cytoplasm contains enzymes catalysing the biosynthesis of RNA was investigated in fractions obtained by differential centrifugation of homogenates of Landschutz ascites-tumour cells. 2. The microsomal fraction was shown to be most active in incorporating UMP residues from [alpha-(32)P]UTP into polyribonucleotide ...
J R, Wykes, R M, Smellie
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Homoiterons and expansion in ribosomal RNAs
FEBS Open Bio, 2015 Ribosomal RNAs in both prokaryotes and eukaryotes feature numerous repeats of three or more nucleotides with the same nucleobase (homoiterons). In prokaryotes these repeats are much more frequent in thermophile compared to mesophile or psychrophile ...
Michael S. Parker +3 more
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Studies on the Specificity of the Enzymic Synthesis of Polyribonucleotides [PDF]
European Journal of Biochemistry, 1967 The purpose of this study was to ascertain whether enzymes having the same function (in this case, polynucleotide phosphorylase), but isolated from two very distant cell types, differed in their synthetic capacities. The enzymes were isolated from B.
F E, Farber, E, Chargaff
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Polyribonucleotides containing a thiophosphate backbone
FEBS Letters, 1969 Polynucleotides resistant to nucleases are of great interest to biochemists. Such polymers would allow the storage of information in a rather stable form and might be useful, e.g., as templates for polymerases and messenger-RNA. So far such polynucleotides have not been prepared.
Eckstein, F., Gindl, H.
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Pyran and Polyribonucleotides: Differences in Biological Activities [PDF]
Antimicrobial Agents and Chemotherapy, 1972 Maleic anhydride-divinyl ether copolymer (pyran) and the polyribonucleotides are both large polyanions with potent antiviral activity. However, they are biologically quite different. Interferon levels of 100 units or more/ml were associated with antiviral activity of polyribonucleotides.
P S, Morahan, W, Regelson, A E, Munson
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