Results 21 to 30 of about 1,913 (163)
Protection of 2′‐Hydroxy Functions of Ribonucleosides [PDF]
, 2000 The main purpose of this article is to discuss 2′‐protection in the context of effective oligoribonucleotide synthesis. Emphasis is placed on the 2′‐protecting groups of choice in the synthesis of oligo‐and polyribonucleotides, and the requirements that ...
Reese, Colin B., Colin B. Reese
core +1 more source
, 2017 The interaction of antitumor drug mitoxantrone (MTX) with double-stranded synthetic RNA homopolymers has been studied by means of spectroscopic (UV-Visible absorption, circular dichroism) techniques.
Rusanna S. Ghazaryan +3 more
core +1 more source
The Journal of Physiology, Volume 604, Issue 16, Page 6943-6958, 15 August 2026.Abstract figure legend Graphical abstract of the proposed Ro5‐4864 mechanism of action via p62‐Keap1‐Nrf2 axis in heart failure. TSPO, the 18‐kDa mitochondrial translocator protein of the outer mitochondrial membrane, can directly interact with p62 (also known as SQSTM1), which is crucial for the degradation of damaged mitochondria by autophagy ...
Daphne A. Diloretto +7 more
wiley +1 more source
, 1998 The DeVoe polarizability theory is used to calculate vibrational circular dichroism (VCD) and infrared (IR) absorption spectra of four polyribonucleotides: poly(rA) · poly(rU), poly(rU) · poly(rA) · poly(rU), poly(rG) · poly(rC), and poly(rC+) · poly(rI)
Moore, Dexter S., Self, Barry D.
core +1 more source
Journal of Extracellular Biology, Volume 5, Issue 3, March 2026.ABSTRACT Gestational diabetes mellitus (GDM) is a common metabolic disorder of pregnancy associated with significant maternal and neonatal morbidity and mortality. Current diagnostic strategies, particularly the oral glucose tolerance test (OGTT), are limited by late detection, variability in diagnostic criteria, and patient burden, highlighting the ...
Mai Ahmed +3 more
wiley +1 more source
Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.HBV DNA integrates in multiple genes including KMT2B in pancreatic cancer. KMT2B upregulation caused by HBV integration or other mechanisms promotes FYN expression via histone H3K4 trimethylation at its promoter region. Increased FYN expression activates the PI3K/Akt signalling pathway, thus driving PDAC cell proliferation, migration and invasion ...
Mengge Li +16 more
wiley +1 more source
Effect of O(2')-methylation on the stability of polynucleotide helices
, 1979 The effect of ribose(O2')-methylation on the stability of (O2')-methylated polyribonucleotide helices has been studied by conformational energy calculations.
Sundaralingam, M., Yathindra, N.
core +1 more source
, 2015 Several homologous polynucleotides have been tested as inhibitors on the reactions catalyzed by avian myeloblastosis virus (AMV) reverse transcriptase, in the presence of polyribonucleotides and 2'-fluorinated polynucleotides as templates ...
Aoyama, H, Juca, M B
core +2 more sources
Mitochondrial Quality Control in Health and Disease
MedComm, Volume 6, Issue 8, August 2025.Mitochondrial quality control (MQC) maintains cellular homeostasis by coordinating various processes such as fission, fusion, mitophagy, and mitochondria‐regulated cell death. Dysregulation of these mechanisms plays a key role in the development of many human diseases.
Lin Ye, Xinzhi Fu, Qi Li
wiley +1 more source
The histochemical demonstration of hydrolase activities with films of homopolyribonucleotides.
, 1975 Films of polycytidylic acid, polyuridylic acid and polyguanylic acid were exposed to tissue sections and the results were compared with those obtained in previous studies on polyadenylic acid and ribonucleic acid.
R Daoust
core +1 more source