Results 51 to 60 of about 1,496,050 (296)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Aliphatic Diacidic Long-Chain C16 Polyesters from 10,16-Dihydroxyhexadecanoic Acid Obtained from Tomato Residual Wastes

open access: yesMolecules, 2019
10,16-dihydroxyhexadecanoic acid obtained from agroresidual tomato waste, was oxidized to produce 7-oxohexadecanedioic acid in good yield (>70%) and purified without oxidation side products in one step.
Daniel Arrieta-Baez   +4 more
doaj   +1 more source

Gig1, a novel antiviral effector involved in fish interferon response [PDF]

open access: yes, 2014
Vertebrate interferon (IFN) response defenses against viral infection through the induction of hundreds of IFN-stimulated genes (ISGs). Most ISGs are conserved across vertebrates; however, little is known about the species-specific ISGs.
Chen, Chen   +7 more
core   +1 more source

Operations and poly-operations in Algebraic Cobordism [PDF]

open access: yes, 2020
We describe all operations from a theory A^* obtained from Algebraic Cobordism of M.Levine-F.Morel by change of coefficients to any oriented cohomology theory B^* (in the case of a field of characteristic zero).
Vishik, Alexander
core   +3 more sources

Distinct Poly(I-C) and Virus-activated Signaling Pathways Leading to Interferon-β Production in Hepatocytes [PDF]

open access: yesJournal of Biological Chemistry, 2005
Innate cellular antiviral defenses are likely to influence the outcome of infections by many human viruses, including hepatitis B and C viruses, agents that frequently establish persistent infection leading to chronic hepatitis, cirrhosis, and liver cancer.
Kui, Li   +4 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Polymeric Forms of Plant Flavonoids Obtained by Enzymatic Reactions

open access: yesMolecules, 2022
Naringenin is one of the flavonoids originating from citrus fruit. This polyphenol is mainly found in grapefruit, orange and lemon. The antioxidant and antimicrobial properties of flavonoids depend on their structure, including the polymeric form.
Malgorzata Latos-Brozio   +2 more
doaj   +1 more source

Senegalese sole (Solea senegalensis) ISG15: molecular characterization and in vivo interplay with viral infections [PDF]

open access: yes, 2015
The interferon-stimulated gene 15 (Isg15) is strongly induced by type I interferon (IFN I), viral infection, and double-stranded RNA (poly I:C) in several fish species, suggesting that Isg15 protein could play a key role in fish innate immunity against ...
Alonso-Sanchez, Maria del Carmen   +5 more
core  

Ab initio study of electron transport in dry poly(G)-poly(C) A-DNA strands

open access: yes, 2010
The bias-dependent transport properties of short poly(G)-poly(C) A-DNA strands attached to Au electrodes are investigated with first principles electronic transport methods.
Chen, X.   +4 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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