Results 61 to 70 of about 39,772,641 (314)
Cal Poly Humboldt Publishing Catalog [PDF]
A catalog of publications from Cal Poly Humboldt.
The Press at Cal Poly Humboldt,
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Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
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Poly(I∶C)-pretreated P14 CD8 T cells have reduced effector function.
(A–B, E–H) WT or IFNαβR KO P14 cells were transferred into congenic mice that were inoculated with HBSS or poly(I∶C), and 1 day later equal numbers of P14 cells were transferred into separate congenic mice subsequently infected with LCMV.
Raymond M. Welsh (170062) +1 more
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Poly(l-lactide) (PLLA)/poly(ε-caprolactone) (PCL) blends traditionally show low ductility because of the immiscibility between PLLA and PCL. In this study, this ductility challenge was addressed by modifying the compatibility between PLLA and PCL using ...
Yang, Yihu +5 more
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Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
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Backrounds: Schizophrenia is a devastating psychiatric disorder with complex symptoms and neurobiology, affecting approximately 1% of the world's population. Studies have shown that exposure to viral and bacterial infections during pregnancy increases the risk of neurodevelopmental disorders including schizophrenia and autism  ...
Taşkıran, Sacide +3 more
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Mice were HBSS- or poly(I∶C)-treated for 1 day. Splenocytes were isolated and either unstimulated, or stimulated ex vivo with IFNβ for 30 min and then stained for (B) pSTAT1,(C) pSTAT3,(D) pSTAT4, and (E) pSTAT5. (A) shows representative histograms gated
Raymond M. Welsh (170062) +1 more
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RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
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Humpback grouper (Cromileptes altivelis) is an economically important fish, but the increasing density of its farming has led to more severe disease outbreaks.
Xiangyu Du +7 more
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Poly(I∶C)-induced impaired proliferation is transient and requires direct effects of type 1 IFN.
(A) Experimental design for poly(I∶C)-induced suppression of proliferation. P14 transgenic CD8 T cells were adoptively transferred into Thy1.2+/Ly5.2+ congenic mice.
Raymond M. Welsh (170062) +1 more
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