Results 251 to 260 of about 279,067 (313)
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Structure of Poly (U)•Poly (A)•Poly (U)
Journal of Biomolecular Structure and Dynamics, 2000The molecular structure of poly (U).poly (A).poly (U) has been determined and refined using the continuous x-ray intensity data on layer lines in the diffraction pattern obtained from an oriented fiber of the RNA. The final R-value for the preferred structure is 0.24, far lower than that for the plausible alternatives.
R, Chandrasekaran +2 more
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Structures for Poly(U).poly(A).poly(U) Triple Stranded Polynucleotides
Nature New Biology, 1973X-ray fibre diffraction studies indicate suitability of triple stranded polynucleotides for biological role.
S, Arnott, P J, Bond
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The Structure of Triple Helical Poly(U)·Poly(A)·Poly(U) Studied by Raman Spectroscopy
Journal of Biomolecular Structure and Dynamics, 1984Using Raman spectroscopy, we examined the ribose-phosphate backbone conformation, the hydrogen bonding interactions, and the stacking of the bases of the poly(U).poly(A).poly(U) triple helix. We compared the Raman spectra of poly(U).poly(A).poly(U) in H2O and D2O with those obtained for single-stranded poly(A) and poly(U) and for double-stranded poly(A)
T, O'Connor, M, Bina
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Poly A-Poly U: An Updated Review
Biopolymers, 1990Poly A:Poly U is a biological response modifier consisting of the twin-chain RNA polymers polyadenylic and polyuridylic acids forming a synthetic polyribonucleotide complex. The compound is endowed with a variety of immunopharmacological activities on both the humoral and cellular components of the immune response and exhibits antitumor effects.
T. Tursz +3 more
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The low temperature reaction of poly U and poly A
Experientia, 1967Es wurde die Temperaturabhangigkeit der Wechselwirkung von Polyriboadenylicsaure mit Polyriboridylicsaure viskosometrisch untersucht. Zeitund Temperaturabhangigkeiten der Viskose deuten an, dass der Zustand der Polymer-Organisation die Reaktion beeinflusst.
D B, Millar, R F, Steiner
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International Journal of Biological Macromolecules, 2003
Differential UV spectroscopy and thermal denaturation were used to study the Mg(2+) ion effect on the conformational equilibrium in poly A.2 poly U (A2U) and poly A . poly U (AU) solutions at low (0.01 M Na(+)) and high (0.1 M Na(+)) ionic strengths.
Victor A, Sorokin +5 more
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Differential UV spectroscopy and thermal denaturation were used to study the Mg(2+) ion effect on the conformational equilibrium in poly A.2 poly U (A2U) and poly A . poly U (AU) solutions at low (0.01 M Na(+)) and high (0.1 M Na(+)) ionic strengths.
Victor A, Sorokin +5 more
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European Journal of Biochemistry, 1968
Some optical and thermodynamic properties of the double helical form of the alternating copolymer poly(A‐U) and the two stranded complex of poly A and poly U are compared. It is shown that their thermal difference spectra are closely similar when that of the latter complex is corrected for the hypochromicity of the poly A formed on denaturation ...
E G, Richards, H, Simpkins
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Some optical and thermodynamic properties of the double helical form of the alternating copolymer poly(A‐U) and the two stranded complex of poly A and poly U are compared. It is shown that their thermal difference spectra are closely similar when that of the latter complex is corrected for the hypochromicity of the poly A formed on denaturation ...
E G, Richards, H, Simpkins
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Association of Poly(A) and Poly(U) Polymerases with Cytoplasmic Ribosomes
European Journal of Biochemistry, 1978Cytoplasmic ribosomes of Ehrlich ascites tumour cells were isolated under conditions where ribonuclease contamination is minimized. These ribosomes displayed poly(A) and poly(U) polymerase activity with [3H]ATP or [3H]UTP as substrates, while incorporation of [3H]GTP or [3H]CTP was not observed.
G I, Milchev, A A, Hadjiolov
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Inhibition of Entry of HIV into Cells by Poly(A)·Poly(U)
AIDS Research and Human Retroviruses, 1993Polyadenylic-polyuridylic acid referred to as poly (A)·poly(U), is a synthetic double-stranded RNA that has been shown to manifest both antitumoral and immunodulatory activities. Previously, we have reported that poly(A)·poly(U) inhibits HIV infection in cell cultures. Here we provide direct evidence to demonstrate that the inhibitory action of poly(A)·
B, Krust, C, Callebaut, A G, Hovanessian
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