Results 271 to 280 of about 279,067 (313)

The interaction of quinacrine with triple-stranded poly(U).poly(A).poly(U).

Nucleic acids symposium series, 1996
The interaction of the antimalarial drug quinacrine (QAC) with triple-stranded poly(U).poly(A).poly(U)(poly(U.A.U)) has been investigated by absorption, fluorescence and circular dichroism (CD) measurements. The results indicate that QAC binds to poly(U.A.U), as well as double-stranded poly (A).poly(U) (poly(A.U)) and poly(I).poly(C) (poly(I.C)). It is
S, Tani, Y, Kubota
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Poly(A):Poly(U); Poly(O8A):Poly(U); Poly(A):Poly(MeNH5U) and poly(O8A):Poly(MeNH5U) versus bida semliki forest virus in chick embryos

Toxicology Letters, 1982
Poly(A):poly(U) (polyadenylic acid:polyuridylic acid hybrid); poly(O8A):poly(U) (poly-8-oxy-adenylic acid:polyuridylic acid hybrid); poly(A):poly(MeNH5U) (polyadenylic acid-5-methylamino uridylic acid hybrid) and poly(O8A):poly(MeNH5U) (poly-8-oxyadenylic acid:poly-5-methylamino uridylic acid hybrid) were studied in chick embryos to compare the ...
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Heats of the helix–coil transitions of the poly A–poly U complexes

Biopolymers, 1968
AbstractThe heats of the conformational transitions of poly (A + U) and poly(A + 2U) were determined in a twin‐cell differential thermal analysis microcalorimeter capable of measuring heat effects of 25–35 meal, in reactions of this type, with a precision of about 3%.
H, Krakauer, J M, Sturtevant
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A Kinetic Study of the Intercalation of Ethidium Bromide into Poly(A)·Poly(U)

The Journal of Physical Chemistry B, 2002
The equilibria and kinetics of the intercalation of ethidium bromide (EB) into poly(A).poly(U) have been studied in aqueous solution (pH = 7.0, 1 M NaCI, 25 °C) by spectrophotometry, spectrofluorimetry, and stopped-flow techniques. The analysis of the binding isotherms yields the site binding constant K = 2.6 x 10 4 M - 1 and the site size n = 2.2 ...
M. L. DAMICO, V. PAIOTTA, SECCO, FERNANDO, VENTURINI, MARCELLA   +3 more
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Structural transitions in poly(A), poly(C), poly(U), and poly(G) and their possible biological roles

Journal of Biomolecular Structure and Dynamics, 2018
The homopolynucleotide (homo-oligonucleotide) tracts function as regulatory elements at various stages of mRNAs life cycle. Numerous cellular proteins specifically bind to these tracts. Among them are the different poly(A)-binding proteins, poly(C)-binding proteins, multifunctional fragile X mental retardation protein which binds specifically both to ...
Margarita I. Zarudnaya, Iryna M. Kolomiets, Andriy L. Potyahaylo, Dmytro M. Hovorun   +3 more
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The separation of three antibody populations from anti-poly(A)·poly(U) antibodies elicited in mice or rabbits and antigenic features of poly(A)·poly(U)

Molecular Immunology, 1982
Anti-poly(A).poly(U) antibodies in ascitic fluid of DDY mice immunized with poly(A).poly(U)-methylated bovine serum albumin complexes were fractionated into three major antibody populations, Ab-1, Ab-2 and Ab-3, by precipitating with poly(I).poly(C), poly(A).poly(U), and poly(A).2 poly(U), respectively.
Y, Kitagawa, E, Okuhara
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Oligo(U)- and poly(U)-containing RNA of wheat embryo

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1980
A UMP-rich RNA fraction was separated from the bulk cellular RNA by affinity chromatography of wheat embryo total RNA. The obtained preparation was heterogeneous and contained polyribonucleotide chain segments which were resistant to RNAase T1 and consisted mainly of UMP residues (87 mol%).
M, Dobrzanska, M, Tomaszewski, J, Buchowicz   +2 more
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Third strand stabilization of poly(U)·poly(A)* poly(U) triplex by the naturally occurring flavone luteolin: A multi-spectroscopic approach

International Journal of Biological Macromolecules, 2017
Naturally occurring flavonoid luteolin (LTN) was found to interact with double stranded poly(A).poly(U) and triple stranded poly(U)·poly(A)*poly(U) with association constants of the order of 104M-1. The association was monitored by various spectroscopic and viscometric techniques. Non-cooperative binding was observed for the association of LTN with two
Richa, Tiwari, Lucy, Haque, Sutanwi, Bhuiya, Suman, Das   +3 more
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The nature of different influence of Cd2+ ions on the conformational equilibrium of triple-stranded polyribonucleotides poly(U)•poly(A)•poly(U) and poly(I)•poly(A)•poly(I) in aqueous solutions

Biophysics, 2007
The influence of Cd2+ ions on the conformational equilibrium of single-stranded (poly(U), poly(A), poly(I)) and triple-stranded polyribonucleotides (A2I, A2U) in aqueous solutions (0.1 M Na+ pH 7) has been investigated using difference UV spectroscopy and thermal denaturation.
V. A. Sorokin, V. A. Valeev, E. L. Usenko, E. A. Andrus, Yu. P. Blagoi   +4 more
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Observations on the kinetics of action of polyspermine-ribonuclease on poly(A)·Poly(U)

Biochimica et Biophysica Acta (BBA) - Enzymology, 1979
Starting from the observation that double-stranded ribonucleic acids are hydrolyzed more rapidly by bovine pancreatic ribonuclease that has been cross-linked to polyspermine, we have made an initial examination of the kinetics of the process. The addition of eight residues of the polyamine serves to strengthen the binding to poly(A).poly(U) 100-fold ...
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