Results 61 to 70 of about 279,067 (313)
Ultrastructural nucleolar alterations induced by an ametantrone - Poly r(A-U) complex
, 1998 The current study has documented changes in the ultrastructure as well as in the intranucleolar distribution of rDNA and rRNA in RT4 (human transitional cell bladder carcinoma) cell nucleoli following a 3-h exposure to toxic doses of 50 μM ametantrone ...
Gilloteaux, Jacques +5 more
core +2 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Synthesis and cell adhesion studies of linear and hyperbranched poly(butyl methacrylate) and poly(t-butyl acrylate) [PDF]
, 2013 A library of polymers/oligomers with three different architectures was synthesised. Short chain, linear oligomers were produced by performing oxidative cleavage on a poly(butyl methacrylate-co-butadiene) polymer.
Cox-Nowak, Kayleigh
core
Involutive representations of coordinate algebras and quantum spaces
Journal of High Energy Physics, 2017 We show that s u 2 $$ \mathfrak{s}\mathfrak{u}(2) $$ Lie algebras of coordinate operators related to quantum spaces with s u 2 $$ \mathfrak{s}\mathfrak{u}(2) $$ noncommutativity can be conveniently represented by SO(3)-covariant poly-differential ...
Tajron Jurić +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecules, 2016 Developing an efficient immobilized enzyme is of great significance for improving the operational stability of enzymes in poly(ε-caprolactone) synthesis.
Hui Ren +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Calorimetric measurement of transition enthalpies in the polynucleotidesystem poly A-poly U
, 1967 Neumann E, Ackermann T. Calorimetric measurement of transition enthalpies in the polynucleotidesystem poly A-poly U. Journal of Physical Chemistry.
Ackermann, Theodor, Neumann, Eberhard
core +1 more source
Marine Drugs, 2018 Alginate lyases are important tools to prepare oligosaccharides with various physiological activities by degrading alginate. Particularly, the bifunctional alginate lyase can efficiently hydrolyze the polysaccharide into oligosaccharides.
Benwei Zhu +3 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source