Results 251 to 260 of about 93,889 (281)

N4-acetylcytidine coordinates with NP1 and CPSF5 to facilitate alternative RNA processing during the replication of minute virus of canines. [PDF]

Nucleic Acids Res
Zhang X, Qin S, Huang F, Liu H, Wang J, Chen Z, Hao H, Ding S, Liu L, Yu B, Liu Y, Liu H, Guan W.   +12 more
europepmc   +1 more source

Protocol for unlocking alternative polyadenylation insights from bulk RNA-seq data with PolyAMiner-Bulk. [PDF]

STAR Protoc
Jonnakuti V, Jonnakuti S, Yalamanchili HK.   +2 more
europepmc   +1 more source

PolyASite v3.0: a multi-species atlas of polyadenylation sites inferred from single-cell RNA-sequencing data. [PDF]

Nucleic Acids Res
Moon Y, Herrmann CJ, Mironov A, Zavolan M.   +3 more
europepmc   +1 more source

ProQ prevents mRNA degradation through inhibition of poly(A) polymerase. [PDF]

Nucleic Acids Res
Bergman S, Birk C, Holmqvist E.
europepmc   +1 more source

Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non-small Cell Lung Cancer. [PDF]

Adv Sci (Weinh)
Jin M, Huang Y, Li B, Wang Y, Li Y, Chen Z, Tang Z, Liu C, Zhang L, Yuan X, Tian J, Liu B.   +11 more
europepmc   +1 more source

A direct RNA-seq-based EBV Latency Transcriptome Offers Insights into the Biogenesis of EBV Gene Products

Mamane-Logsdon A, Zane I, Chong JS, Chou OHI, Huang J, Rawal M, Gillman AC, Wongwiwat W, Saleban M, Donovan-Banfield I, Matthews DA, White RE.   +11 more
europepmc   +1 more source

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Alternative polyadenylation regulation: insights from sequential polyadenylation

Transcription, 2022
The processing of the proximal and distal poly(A) sites in alternative polyadenylation (APA) has long been thought to independently occur on pre-mRNAs during transcription. However, a recent study by our groups demonstrated that the proximal sites for many genes could be activated sequentially following the distal ones, suggesting a multi-cleavage-same-
Peng Tang, Yu Zhou
openaire   +2 more sources

The biochemistry of polyadenylation

Trends in Biochemical Sciences, 1996
During the synthesis of mRNA in the nucleus, 3'-ends are generated by endonucleolytic cleavage followed by polyadenylation. The machinery responsible for this simple reaction is surprisingly complex. In vitro reconstitution of 3'-end processing has demonstrated the importance of cooperative interactions in RNA recognition and catalysis.
Wahle, E., Keller, W.
openaire   +4 more sources

Cleavage of the polyadenylate-rich region of polyadenylate-rich RNA

Biochemical and Biophysical Research Communications, 1972
Abstract The polyadenylate-rich portion of rapidly-labeled polyribosomal RNA isolated from lymphocytes or adrenal cortex was cleaved by a ribonuclease co-purifying with this RNA and retaining activity despite exposure to SDS and phenol. A ribosomal factor which inhibited the digestion of polyriboadenylate-rich RNA by the associated ribonuclease was ...
Michael G. Rosenfeld, Lucille A. Perkins, Itamar B. Abrass   +2 more
openaire   +3 more sources