Results 151 to 160 of about 106,104 (288)
VIEW, EarlyView.Ovarian cancer has been linked to the microbiome as a potential environmental contributor, but how this association relates to tumor progression remains unclear. By comparing tumor and nontumor tissues, we identified a severity‐associated microbial and metabolic signature and showed that probiotics can partially restore immune balance and slow tumor ...
Chanyuan Li +11 more
wiley +1 more source
Anion-exchanging Water-insoluble Polyamine Complex of Copper
, 1958 Saburo Nonogaki +2 more
openalex +2 more sources
British Journal of Haematology, EarlyView.We show how the loss of activity of the translation initiation factor EIF5A2—either through gene hypermethylation or pharmacologic inhibition of its highly specific hypusine post‐translational modification—induces venetoclax sensitivity in acute myeloid leukaemia (AML) cells.
Eva Crespo‐García +5 more
wiley +1 more source
Polyamines and abiotic stress tolerance in plants [PDF]
, 2010 Sarvajeet Singh Gill, Narendra Tuteja
openalex +1 more source
The return of metabolism: biochemistry and physiology of glycolysis
Biological Reviews, EarlyView.ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Molecular Mechanisms of the Chemopreventive Effects of Resveratrol and Its Analogs in Colorectal Cancer: Key Role of Polyamines? [PDF]
, 2004 Freya Wolter +2 more
openalex +1 more source
A YAP/TAZ–CDC6 Axis Initiates and Maintains Malignant Transformation
Cancer Science, EarlyView.This study demonstrates that constitutive activation of YAP or TAZ is sufficient to induce and maintain malignant transformation in fibroblasts, identifying them as essential oncogenic drivers. Transcriptomic and functional analyses revealed CDC6 as a critical downstream effector of YAP/TAZ, with elevated expression linked to tumorigenesis across ...
David Nduru +5 more
wiley +1 more source
The FEBS Journal, EarlyView.A novel assay evaluates plant biostimulants targeting the brassinosteroid receptor BRI1, a central component in plant growth and development. By expressing BRI1 in fission yeast, functional activation by brassinolide (BL) was enabled. Transcriptomic profiling identified BL‐responsive genes, leading to a GFP‐based reporter system. This platform offers a
Maribel Marquina +9 more
wiley +1 more source
Supramolecular modulation of action of polyamine on enzyme/DNA interactions
, 2005 Hiroyuki Isobe +5 more
openalex +2 more sources
The FEBS Journal, EarlyView.Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley +1 more source