Opening closed inward rectifier potassium channel doors
Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger +3 more
wiley +1 more source
ODC1 Polyamine Metabolism Drives Prostate Cancer via AKT and Splicing. [PDF]
Ma J +6 more
europepmc +1 more source
Defining the tumor microenvironment of non‐small cell lung cancer
The tumor microenvironment (TME) in non‐small cell lung cancer is highly heterogeneous, both at a patient level and tumor microenvironment resolution. Defining the tumor microenvironment from patient‐responders and non‐responders will aid in the development of targeted therapeutics specific for each individual patient.
Kidane Siele Embaye +5 more
wiley +1 more source
Functional Analysis of Tomato SPDS in Response to Osmotic Stress. [PDF]
Cheng L +8 more
europepmc +1 more source
How to be young at heart? miR-22 as a potential therapeutic target to boost autophagy and protect the old myocardium [PDF]
DE FALCO, Elena +3 more
core +2 more sources
ABSTRACT This study was conducted to determine the effects of priming safflower cultivar (Askon 42) with various doses (0, 5, 10, 15 mM) of 3 different amino acids (methionine, lysine, tyrosine) against salt stress (0, 50, 100, 150 mM) in terms of investigated parameters.
Mehtap Gürsoy
wiley +1 more source
Methyl caffeate exhibits dual functionality against Pseudomonas syringae pv. tomato. It directly disrupts bacterial membrane integrity, induces reactive oxygen species accumulation, and inhibits flagellar motility and the type III secretion system. Concurrently, it primes plant defence by activating defence‐related gene expression and enzyme activities,
Yarui Yang +11 more
wiley +1 more source
Adaptive crosstalk between polyamine metabolism, translation, and autophagy sustains energy homeostasis in mammals during starvation: a scoping review. [PDF]
Karimi K +4 more
europepmc +1 more source
A mitochondrial machinery for membrane translocation of precursor proteins [PDF]
Neupert, Walter, Pfanner, Nikolaus
core +1 more source
LBX1 alters polyamine pathway in adolescent idiopathic scoliosis - a new therapeutic target to mitigate curve progression. [PDF]
Zhang Z +21 more
europepmc +1 more source

